• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Materials Science & Engineering >Metallic implant biomaterials
【24h】

Metallic implant biomaterials

机译：金属植入物生物材料

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Human tissue is structured mainly of self-assembled polymers (proteins) and ceramics (bone minerals), with metals present as trace elements with molecular scale functions. However, metals and their alloys have played a predominant role as structural biomaterials in reconstructive surgery, especially orthopedics, with more recent uses in non-osseous tissues, such as blood vessels. With the successful routine use of a large variety of metal implants clinically, issues associated with long-term maintenance of implant integrity have also emerged. This review focuses on metallic implant biomaterials, identifying and discussing critical issues in their clinical applications, including the systemic toxicity of released metal ions due to corrosion, fatigue failure of structural components due to repeated loading, and wearing of joint replacements due to movement. This is followed by detailed reviews on specific metallic biomaterials made from stainless steels, alloys of cobalt, titanium and magnesium, as well as shape memory alloys of nickel-titanium, silver, tantalum and zirconium. For each, the properties that affect biocompatibility and mechanical integrity (especially corrosion fatigue) are discussed in detail. Finally, the most critical challenges for metallic implant biomaterials are summarized, with emphasis on the most promising approaches and strategies.
机译：人体组织主要由自组装的聚合物（蛋白质）和陶瓷（骨矿物质）构成，金属以微量元素的形式存在，具有分子尺度的功能。然而，金属及其合金在重建手术，尤其是整形外科中作为结构生物材料起着主要作用，最近在非骨组织（如血管）中得到了使用。随着临床上成功地常规使用各种金属植入物，还出现了与长期保持植入物完整性相关的问题。这篇综述的重点是金属植入物生物材料，确定并讨论其临床应用中的关键问题，包括由于腐蚀而释放的金属离子的全身毒性，由于反复加载而导致的结构部件的疲劳失效以及由于运动引起的关节置换件的磨损。接下来是对由不锈钢，钴，钛和镁的合金以及镍钛，银，钽和锆的形状记忆合金制成的特定金属生物材料的详细评论。对于每种材料，都将详细讨论影响生物相容性和机械完整性（特别是腐蚀疲劳）的特性。最后，总结了金属植入物生物材料最关键的挑战，重点是最有希望的方法和策略。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号