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A Method for the Evaluation of Femoral Head Trabecular Bone Compressive Properties

机译：股骨头小梁骨压缩特性的评估方法

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摘要

We addressed the importance of defining a mechanical testing methodology for the compression of human trabecular bone specimens. In fact, currently there are several protocols to test trabecular bone, but a single, standard and validate method has not been accepted yet. In our work, human femoral epiphyses collected from patients with osteoporosis (fragility fractures) and hip osteoarthritis, submitted to total hip replacement surgery, were used.The aims of our work were to develop a mechanical testing methodology for the compression of trabecular bone specimens taking into account the optimization of bone extrinsic and intrinsic variables, in order to establish a patient bone sample database with clinical, structural and mechanical information.Extrinsic variables, such as the effect of specimen preparation, with particular focus on the dimensions of test specimens, and others associated with the compression test, such as the method employed to determine specimen deformation, and hence strain, were evaluated. Also, a new device used to withhold the specimens was developed and tested by the present authors. Although each specimen showed a unique behaviour, even when comparing compression curves between patients from the same disease group, implicating additional complexity and difficulty in the data analysis, the authors managed to assemble the results in two groups related with a possible difference in the deformation mechanisms occurring after yielding.
机译：我们讨论了定义机械测试方法以压缩人小梁骨标本的重要性。实际上，目前有几种测试小梁骨的方案，但是尚未接受一种单一的，标准且有效的方法。在我们的工作中，使用了从骨质疏松症（易碎性骨折）和髋骨关节炎患者中收集的人类股骨骨ses，并进行了全髋关节置换手术。我们的工作目的是开发一种机械测试方法来压缩小梁骨标本考虑优化骨骼外在和内在变量，以便建立具有临床，结构和力学信息的患者骨骼样本数据库外在变量，例如标本制备的效果，尤其着重于试样的尺寸，以及评估了与压缩试验相关的其他方法，例如用于确定试样变形和应变的方法。另外，本作者开发并测试了一种用于保留样本的新设备。尽管每个标本都表现出独特的行为，但即使在比较同一疾病组患者之间的压缩曲线时，也暗示了数据分析的额外复杂性和难度，作者设法将结果归为两组，但变形机制可能存在差异发生在屈服之后。

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  • 来源
    《Materials science forum》 |2013年第1期|3-8|共6页
  • 作者

    I. Aleixo; A.C. Vale; M. Lucio; P.M. Amaral; L.G. Rosa; J. Caetano-Lopes; A. Rodrigues; H. Canhao; $J.E. Fonseca; M.F. Vaz;

  • 作者单位

    Institute de Ciencia e Engenharia de Materials e Superficies, Departamento de Engenharia Mecinica, Institute Superior Tecnico, UTL, Av.Rovisco Pais, 1049-001 Lisboa, Portugal,Rheumatology Research Unit, Institute de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, 1649-028 Lisboa, Portugal;

    Institute de Ciencia e Engenharia de Materials e Superficies, Departamento de Engenharia Mecinica, Institute Superior Tecnico, UTL, Av.Rovisco Pais, 1049-001 Lisboa, Portugal,Rheumatology Research Unit, Institute de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, 1649-028 Lisboa, Portugal;

    Institute de Ciencia e Engenharia de Materials e Superficies, Departamento de Engenharia Mecinica, Institute Superior Tecnico, UTL, Av.Rovisco Pais, 1049-001 Lisboa, Portugal,Rheumatology Research Unit, Institute de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, 1649-028 Lisboa, Portugal;

    Institute de Ciencia e Engenharia de Materials e Superficies, Departamento de Engenharia Mecinica, Institute Superior Tecnico, UTL, Av.Rovisco Pais, 1049-001 Lisboa, Portugal;

    Institute de Ciencia e Engenharia de Materials e Superficies, Departamento de Engenharia Mecinica, Institute Superior Tecnico, UTL, Av.Rovisco Pais, 1049-001 Lisboa, Portugal;

    Rheumatology Research Unit, Institute de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, 1649-028 Lisboa, Portugal;

    Rheumatology Research Unit, Institute de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, 1649-028 Lisboa, Portugal,Servico de Reumatologia e Doencas Osseas Metabdlicas, Hospital de Santa Maria, 1649-035 Lisboa, Portugal;

    Rheumatology Research Unit, Institute de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, 1649-028 Lisboa, Portugal;

    Rheumatology Research Unit, Institute de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, 1649-028 Lisboa, Portugal,Servico de Reumatologia e Doencas Osseas Metabdlicas, Hospital de Santa Maria, 1649-035 Lisboa, Portugal;

    Institute de Ciencia e Engenharia de Materials e Superficies, Departamento de Engenharia Mecinica, Institute Superior Tecnico, UTL, Av.Rovisco Pais, 1049-001 Lisboa, Portugal;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    trabecular bone; mechanical properties; compression.;

    机译：小梁骨;力学性能;压缩;

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