Advances in apoptotic mediated proteolysis in meat tenderisation

Caroline M. Kemp; Tim Parr

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Advances in apoptotic mediated proteolysis in meat tenderisation

机译：肉软化中凋亡介导的蛋白水解研究进展

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Meat tenderness is considered to be one of the most important attributes of meat quality; however it is also one of the most variable. Ultimate meat tenderness is influenced by the amount of intramuscular connective tissue, the length of the sarcomere and also the proteolytic potential of the muscle. Post-mortem proteolysis by endogenous proteases causes the weakening of myofibril structures and associated proteins, which results in tenderisation. The caspase proteolytic system was first identified to be a potential contributor to postmortem proteolysis and tenderisation in 2002. Since then research has both supported and challenged this hypothesis. The purpose of this review is to examine the experimental evidence available for caspases' involvement in post-mortem proteolysis, and to highlight cross-talk between this proteolytic system and the calpain system, a known contributor to meat tenderisation.

机译：肉的嫩度被认为是肉质最重要的属性之一。但是它也是变化最大的之一。最终的肉嫩度受肌肉内结缔组织的数量，肌节的长度以及肌肉的蛋白水解潜能的影响。内源蛋白酶的验尸蛋白水解作用导致肌原纤维结构和相关蛋白的减弱，从而导致嫩化。 caspase蛋白水解系统于2002年首次被确定为死后蛋白水解和嫩化的潜在贡献者。此后，研究一直支持并挑战了这一假设。这篇综述的目的是检查有关胱天蛋白酶参与验尸蛋白水解的实验证据，并强调该蛋白水解系统和钙蛋白酶系统之间的相互影响，钙蛋白酶系统是导致肉嫩化的已知因素。

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《Meat Science》 |2012年第3期|p.252-259|共8页
作者
Caroline M. Kemp; Tim Parr;
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作者单位

Central Community College, Grand Island, NE 68802, USA;

Division of Nutritional Sciences, School of Biosciences, Sutton Bonington Campus, The University of Nottingham, Leicestershire, LE12 5RD, UK;

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收录信息美国《科学引文索引》(SCI);
原文格式 PDF
正文语种 eng
中图分类
关键词
caspases; apoptosis; post-mortem proteolysis; meat tenderisation;

机译：半胱氨酸蛋白酶细胞凋亡验尸蛋白水解;肉嫩化;

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专利

1. Factors contributing to proteolysis and disruption of myofibrillar proteins and the impact on tenderisation in beef and sheep meat [J] . D. L. HopkinsABC and J. M. ThompsonA Crop and Pasture Science . 2002,第2期

机译：导致肌原纤维蛋白水解和破坏以及对牛肉和羊肉嫩化的影响的因素
2. A new insight into meat toughness of callipyge lamb loins - The relevance of anti-apoptotic systems to decreased proteolysis [J] . Traci Cramer, Moriah L. Penick, Jolena N. Waddell, Meat Science . 2018,第juna期

机译：剖腹羊腿肉韧性的新见解-抗凋亡系统与降低蛋白水解的相关性
3. Caspase‐mediated proteolysis during apoptosis: insights from apoptotic neutrophils [J] . Casciola-Rosen Livia, Rosen Antony, Sanghavi Darshak M, FEBS Letters . 1998,第2期

机译：凋亡过程中半胱天冬酶介导的蛋白水解：来自凋亡中性粒细胞的见解
4. Effect of plant mediated proteolysis on protein degradation among ten diploid perennial ryegrass (Loliumperenne L.) genotypes [C] . Losche M., Salama H., Gierus M., General Meeting of the European Grassland Federation . 2008

机译：植物介导的蛋白水解对十二二龙（Loliumperenne L.）基因型蛋白质降解蛋白质降解的影响
5. Differential expression of pro-apoptotic and anti-apoptotic genes during diclofenac-induced oxidative stress-mediated nephrotoxicity in vivo. [D] . Bhatt, Shruti. 2009

机译：在双氯芬酸诱导的体内氧化应激介导的肾毒性过程中促凋亡和抗凋亡基因的差异表达。
6. γ-Secretase Activity Is Required for Regulated Intramembrane Proteolysis of Tumor Necrosis Factor (TNF) Receptor 1 and TNF-mediated Pro-apoptotic Signaling [O] . Jyoti Chhibber-Goel, Caroline Coleman-Vaughan, Vishal Agrawal, 2016

机译：γ分泌酶活性是调节肿瘤坏死因子（TNF）受体1和TNF介导的促凋亡信号传导的膜内蛋白水解所必需的
7. γ-Secretase Activity Is Required for Regulated Intramembrane Proteolysis of Tumor Necrosis Factor (TNF) Receptor 1 and TNF-mediated Pro-apoptotic Signaling [O] . Jyoti Chhibber-Goel, Caroline Coleman-Vaughan, Vishal Agrawal, 2016

机译：γ-分泌酶活性是肿瘤坏死因子（TNF）受体1和TNF介导的促细胞凋亡信号传导的调节肠道蛋白分解

Advances in apoptotic mediated proteolysis in meat tenderisation

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