Hydrogen water intake via tube-feeding for patients with pressure ulcer and its reconstructive effects on normal human skin cells in vitro

Qiang Li; Shinya Kato; Daigo Matsuoka; Hiroshi Tanaka; Nobuhiko Miwa

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Hydrogen water intake via tube-feeding for patients with pressure ulcer and its reconstructive effects on normal human skin cells in vitro

机译：压力性溃疡患者通过管饲摄入的氢水及其对正常人皮肤细胞的体外重建作用

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Background Pressure ulcer (PU) is common in immobile elderly patients, and there are some research works to investigate a preventive and curative method, but not to find sufficient effectiveness. The aim of this study is to clarify the clinical effectiveness on wound healing in patients with PU by hydrogen-dissolved water (HW) intake via tube-feeding (TF). Furthermore, normal human dermal fibroblasts OUMS-36 and normal human epidermis-derived cell line HaCaT keratinocytes were examined in vitro to explore the mechanisms relating to whether hydrogen plays a role in wound-healing at the cellular level.

机译：背景技术压疮（PU）在无法移动的老年患者中很常见，有一些研究工作在研究预防和治愈方法，但没有找到足够的疗效。这项研究的目的是阐明通过通过管饲（TF）摄入氢溶解水（HW）来治疗PU患者的伤口愈合的临床效果。此外，在体外检查了正常人真皮成纤维细胞OUMS-36和正常人表皮来源的细胞系HaCaT角质形成细胞，以探索与氢在细胞水平上是否在伤口愈合中起作用有关的机制。

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《Medical Gas Research》 |2013年第1期|1-17|共17页
作者
Qiang Li; Shinya Kato; Daigo Matsuoka; Hiroshi Tanaka; Nobuhiko Miwa;
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正文语种 eng
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关键词
Hydrogen-dissolved water; Pressure ulcer; Wound healing; Type-I collagen; Reactive oxygen species;

机译：氢溶解水;压疮;伤口愈合;I型胶原;活性氧;

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1. Hydrogen water intake via tube-feeding for patients with pressure ulcer and its reconstructive effects on normal human skin cells in vitro [J] . Qiang Li, Shinya Kato, Daigo Matsuoka, Medical Gas Research . 2013,第1期

机译：压力性溃疡患者通过管饲摄入的氢水及其对正常人皮肤细胞的体外重建作用
2. Measurement of NF-κB in normal and reconstructed human skin in vitro [J] . T. SUN, J. W. HAYCOCK, M. SZABO, Journal of Materials Science. Materials in Medicine . 2004,第7期

机译：正常和重建人体皮肤中NF-κB的体外测量
3. Scientific Opinion on the substantiation of health claims related to wheat germ oil and maintenance of normal blood pressure (ID 1386), maintenance of normal blood cholesterol concentrations (ID 599, 2618), maintenance of normal (fasting) blood concentrations of triglycerides (ID 2618), protection of the skin from photo‐oxidative (UV‐induced) damage (ID 600), maintenance of normal skin hydration (ID 600, 1390), maintenance of normal bone (ID 1389), contribution to normal neurological function (ID 1387), contribution to normal cognitive function (ID 1394), contribution to normal fertility (ID 1392), relief of menstrual pain (ID 1395), “digestive system” (ID 1388) and protection of cells from premature aging (ID 1393, 2616) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 [J] . EFSA Journal . 2010,第10期

机译：关于证实与小麦胚芽油和维持正常血压（ID 1386），维持正常血液胆固醇浓度（ID 599、2618），维持正常（禁食）血液甘油三酸酯浓度（ID 2618）有关的健康主张的科学意见），保护皮肤免受光氧化（UV诱导）损伤（ID 600），维持正常的皮肤水合作用（ID 600、1390），维持正常的骨骼（ID 1389），对正常的神经功能有贡献（ID 1387）），对正常认知功能的贡献（ID 1394），对正常生育力的贡献（ID 1392），月经疼痛的缓解（ID 1395），“消化系统”（ID 1388）以及保护细胞免于过早衰老（ID 1393、2616）），根据（EC）1924/2006号法规第13（1）条
4. Effects of cyclic stretch on early response gene expressions in normal human pulmonary artery endothelial cells in vitro [C] . 2010 IEEE International Conference on Bioinformatics and Biomedicine Workshops . 2010

机译：循环拉伸对正常人肺动脉内皮细胞早期反应基因表达的影响
5. New functional markers of human cutaneous cells in reconstructed skin in vitro. [D] . Cvetkovska, Bisera. 2004

机译：体外重建皮肤中人类皮肤细胞的新功能标记。
6. Hydrogen water intake via tube-feeding for patients with pressure ulcer and its reconstructive effects on normal human skin cells in vitro [O] . Qiang Li, Shinya Kato, Daigo Matsuoka, 2013

机译：压力性溃疡患者通过管饲摄入的氢水及其对正常人皮肤细胞的体外重建作用
7. Hydrogen water intake via tube-feeding for patients with pressure ulcer and its reconstructive effects on normal human skin cells in vitro [O] . Qiang Li, Shinya Kato, Daigo Matsuoka, 2013

机译：压力性溃疡患者通过管饲摄入的氢水及其对正常人皮肤细胞的体外重建作用

Hydrogen water intake via tube-feeding for patients with pressure ulcer and its reconstructive effects on normal human skin cells in vitro

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