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首页> 外文期刊>Michigan Academician >Recent Activity of the Retrotransposable B2 Element in Hamsters and Its Use as a Phylogenetic Marker
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Recent Activity of the Retrotransposable B2 Element in Hamsters and Its Use as a Phylogenetic Marker

机译:仓鼠中可逆转座B2元素的最新活性及其作为系统发生标记的用途

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摘要

A recent analysis of DNA sequences of hamsters, in the rodent subfamily Cricetinae (family Cricetidae, superfamily Muroidea), generated a significant phylogenetic restructuring among the genera Tscherkia, Cricetus, Allocricetulus and Cricetulus. We present an analysis of this group of hamsters using retrotransposons as phylogenetic markers to further assess the modified phylogeny. Retrotransposons represent a group of transposable elements that integrate into new genomic locations via an RNA intermediate. The novel use of this tool is that organisms that share a specific retro-transposon integration should share a common ancestor. We present the first examples of recent retrotransposon integrations in the hamster genome and provide support for the revised phylogenetic relationship of hamsters. This study demonstrates that retrotransposons can be valuable tools in ascertaining phylogenetic relationships.
机译:最近对啮齿动物亚科Cricetinae(C科,超科Muroidea)中仓鼠DNA序列的分析在Tscherkia,Cricetus,Allocricetulus和Cricetulus属中产生了重要的系统发育重组。我们目前使用反转录转座子作为系统发育标记对这组仓鼠进行分析,以进一步评估修饰的系统发育。逆转座子代表一组可转座元件,它们通过RNA中间体整合到新的基因组位置。该工具的新颖用途是,共享特定反转录转座子整合的生物应共享同一祖先。我们介绍仓鼠基因组中最近的反转录转座子整合的第一个例子,并为仓鼠的系统发生关系的修订提供支持。这项研究表明,反转录转座子可以是确定系统发育关系的有价值的工具。

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