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首页> 外文期刊>Nanobiotechnology, IET >Antimicrobial activity of functionalised carbon nanotubes against pathogenic microorganisms
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Antimicrobial activity of functionalised carbon nanotubes against pathogenic microorganisms

机译：官能化碳纳米管对致病微生物的抗菌活性

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摘要

Carbon nanotubes represent one of the best examples of novel nanostructures, exhibit a range of extraordinary physical properties, strong antimicrobial activity and can pierce bacterial cell walls. This investigation handles the antimicrobial activity of functionalised multiwall carbon nanotubes (F-MWNTs) as an alternative antimicrobial material compared to the commercial antibiotics. Antibacterial activities of F-MWNTs are investigated through two different kinds of bacteria,E. coliandS. aureus. The results demonstrate that the best concentration of F-MWNTs for the maximum inhibition and antibacterial functionality is 80 and 60 mu g/ml forE. coliandS. aureus, respectively. The transmission electron microscope reveals the morphological changes damage mechanism for the cellular reliability on these microorganisms. F-MWNTs are capable of biologically isolating the cell from their microenvironment, contributing to the development of toxic substances and placing the cell under oxidative stress leading to cellular death. The efficiency of F-MWNTs is compared with the common antibiotics and shows an enhancement in the inhibitory effect with percentages reaches 85%. To account for the bactericidal performance of F-MWNTs towards these pathogens, the dielectric conductivity and the bacterial growth measurements are conducted. The present study endeavour that F-MWNTs could be exploited in biomedical devices and altering systems for hospital and industrial cleaning applications.
机译：碳纳米管代表新型纳米结构的最佳实例之一，表现出一系列非凡的物理性质，强抗微生物活性并且可以刺穿细菌细胞壁。与商业抗生素相比，该研究处理官能化多壁碳纳米管（F-MWNT）作为替代抗微生物材料的抗微生物活性。通过两种不同的细菌来研究F-MWNT的抗菌活性，例如，e。康兰人。金黄色葡萄球菌。结果表明，最大抑制和抗菌官能团的最佳浓度为80至60μg/ ml。康兰人。金黄色葡萄球菌。透射电子显微镜揭示了这些微生物细胞可靠性的形态变化损伤机制。 F-MWNT能够从其微观环境中生物学隔离细胞，有助于毒性物质的发育，并将细胞放置在导致细胞死亡的氧化应激下。将F-MWNT的效率与普通抗生素进行比较，并显示抑制效果的增强百分比达到85％。为了考虑F-MWNTs对这些病原体的杀菌性能，进行介电导率和细菌生长测量。目前的研究努力在生物医学装置中利用F-MWNT和用于医院和工业清洁应用的改变系统。

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