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Impartation of apatite-forming ability to chitosan nanofibres by using apatite nuclei

机译:通过使用磷灰石核来赋予含壳聚糖纳米纤维的磷灰石形成能力

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摘要

Chitosan nanofibre-apatite nuclei composites obtained by mixing apatite nuclei which possess high apatite-forming ability with chitosan nanofibre have been expected to be novel bone restorative materials with suitable properties such as light weight, low coefficient of thermal expansion, high mechanical strength, biocompatibility and bioactivity. In this study, the authors prepared three types of apatite nuclei by changing the reaction time aimed to optimise their crystallinity and fabricated their composites with chitosan nanofibre. In order to evaluate the bioactivity in vitro, the authors tested apatite-forming ability in simulated body fluid. As a result, the materials showed enough apatite-forming ability in a short time by mixing chitosan nanofibre and apatite nuclei with extremely low crystallinity and their high reactivity in simulated body fluid.
机译:通过混合具有高磷灰石形成能力的磷灰烷纳米纤维磷灰石复合材料,其具有高磷酸盐纳米纤维的高磷灰石形成能力,是新的骨恢复材料,具有适当的性能,如重量轻,热膨胀系数低,机械强度高,生物相容性高,机械强度高,生物相容性生物活性。在这项研究中,作者通过改变反应时间来制备三种类型的磷灰石核,旨在优化它们的结晶度并用壳聚糖纳米纤维制造它们的复合材料。为了评估体外生物活性,作者在模拟体液中测试了磷灰石形成能力。结果,通过将壳聚糖纳米纤维和磷灰石核混合在短时间内,材料在短时间内显示出足够的磷灰石形成能力,以及它们在模拟体液中的高反应性。

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