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首页> 外文期刊>Nanobiotechnology, IET >Solvothermal-assisted green synthesis of hybrid Chi-Fe3O4 nanocomposites: a potential antibacterial and antibiofilm material
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Solvothermal-assisted green synthesis of hybrid Chi-Fe3O4 nanocomposites: a potential antibacterial and antibiofilm material

机译:杂交Chi-Fe3O4纳米复合材料的溶剂热辅助绿色合成:抗菌和抗菌材料

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In this present study, a hybrid Chi-Fe3O4 was prepared, characterised and evaluated for its antibacterial and antibiofilm potential against Staphylococcus aureus and Staphylococcus marcescens bacterial pathogens. Intense peak around 260 nm in the ultraviolet-visible spectrum specify the formation of magnetite nanoparticles. Spherical-shaped particles with less agglomeration and particle size distribution of 3.78-46.40 nm were observed using transmission electron microscopy analysis and strong interaction of chitosan with the surface of magnetite nanoparticles was studied using field emission scanning microscopy (FESEM). X-ray diffraction analysis exhibited the polycrystalline and spinel structure configuration of the nanocomposite. Presence of Fe and O, C and Cl elements were confirmed using energy dispersive X-ray microanalysis. Fourier transform infrared spectroscopic analysis showed the reduction and formation of Chi-Fe3O4 nanocomposite. The antibacterial activity by deformation of the bacterial cell walls on treatment with Chi-Fe3O4 nanocomposite and its interaction was visualised using FESEM and the antibiofilm activity was determined using antibiofilm assay. In conclusion, this present study shows the green synthesis of Chi-Fe3O4 nanocomposite and evaluation of its antibacterial and antibiofilm potential, proving its significance in medical and biological applications
机译:在本研究中,制备杂交Chi-Fe3O4,特征和评估其对金黄色葡萄球菌和葡萄球菌的抗菌和抗葡萄球菌细菌病原体的抗菌和抗菌剂。紫外线可见光谱中260nm大约260nm强的峰值指定了磁铁矿纳米颗粒的形成。使用透射电子显微镜分析观察具有较少聚集和粒度分布的球形颗粒3.78-46.40nm,使用现场发射扫描显微镜(FeSem)研究了壳聚糖与磁铁矿纳米颗粒表面的强相互作用。 X射线衍射分析表现出纳米复合材料的多晶和尖晶石结构构型。使用能量分散X射线微基分析确认Fe和O,C和Cl元件的存在。傅里叶变换红外光谱分析显示CHI-Fe3O4纳米复合材料的还原和形成。使用FeSem测定通过Chi-Fe3O4纳米复合物处理的细菌细胞壁的变形抗菌活性,并使用抗体和抗菌活性测定抗菌活性。使用抗菌器测定法测定抗菌活性。总之,本研究表明,Chi-Fe3O4纳米复合材料的绿色合成和其抗菌和抗菌和抗菌和抗菌潜力的评价,证明了其在医学和生物学应用中的重要性

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