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首页> 外文期刊>Nanobiotechnology, IET >Biogenic synthesis, optimisation and antibacterial efficacy of extracellular silver nanoparticles using novel fungal isolate Aspergillus fumigatus MA
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Biogenic synthesis, optimisation and antibacterial efficacy of extracellular silver nanoparticles using novel fungal isolate Aspergillus fumigatus MA

机译：新型真菌分离烟曲霉MA的胞外银纳米粒子的生物合成，优化和抗菌功效

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摘要

To eliminate the elaborate processes employed in other non-biological-based protocols and low cost production of silver nanoparticles (AgNPs), this study reports biogenic synthesis of AgNPs using silver salt precursor with aqueous extract of Aspergillus fumigates MA. Influence of silver precursor concentrations, concentration ratio of fungal extract and silver nitrate, contact time, reaction temperature and pH are evaluated to find their effects on AgNPs synthesis. Ultraviolet-visible spectra gave surface plasmon resonance at 420 nm for AgNPs. Fourier transform infrared spectroscopy and X-ray diffraction techniques further confirmed the synthesis and crystalline nature of AgNPs, respectively. Transmission electron microscopy observed spherical shapes of synthesised AgNPs within the range of 3-20 nm. The AgNPs showed potent antimicrobial efficacy against various bacterial strains. Thus, the results of the current study indicate that optimisation process plays a pivotal role in the AgNPs synthesis and biogenic synthesised AgNPs might be used against bacterial pathogens; however, it necessitates clinical studies to find out their potential as antibacterial agents.
机译：为了消除在其他非基于生物的方案中使用的复杂工艺以及银纳米颗粒（AgNPs）的低成本生产，这项研究报告了使用银盐前体与熏蒸曲霉MA的水提取物进行AgNP的生物合成。评估了银前驱物浓度，真菌提取物和硝酸银的浓度比，接触时间，反应温度和pH值的影响，以发现它们对AgNPs合成的影响。紫外线可见光谱给出了AgNPs在420 nm处的表面等离子体共振。傅里叶变换红外光谱和X射线衍射技术分别进一步证实了AgNPs的合成和晶体性质。透射电子显微镜观察到合成AgNP的球形在3-20nm范围内。 AgNPs显示出对各种细菌菌株的有效抗微生物功效。因此，目前的研究结果表明，优化过程在AgNPs的合成中起着关键作用，而生物合成的AgNPs可以用于抵抗细菌病原体。然而，有必要进行临床研究以发现其作为抗菌剂的潜力。

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