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首页> 外文期刊>Nanobiotechnology, IET >Biosynthesis of silver nanoparticles using aqueous extract of silky hairs of corn and investigation of its antibacterial and anticandidal synergistic activity and antioxidant potential
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Biosynthesis of silver nanoparticles using aqueous extract of silky hairs of corn and investigation of its antibacterial and anticandidal synergistic activity and antioxidant potential

机译：玉米丝状毛水提物生物合成银纳米颗粒及其抑菌和增生协同作用及抗氧化能力的研究

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This paper investigated the green synthesis of silver nanoparticles (AgNPs) using aqueous extract of silky hairs of corn (Zea mays L.) which is a waste material of the crop, as both a reducing and stabilising/capping agent. The AgNPs were characterised by UV-visible spectroscopy, scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDX), thermogravimetric analysis (TGA), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FT-IR). The average size of AgNPs was found to be 249.12 nm. The AgNPs displayed strong antibacterial activity against five different foodborne pathogenic bacteria with diameter of inhibition zones ranged between (9.23 - 12.81 mm). It also exhibited potent synergistic antibacterial activity together with standard antibiotics, kanamycin (10.6 - 13.65 mm inhibition zones) and rifampicin (10.02 - 12.86 mm inhibition zones) and anticandidal activity with amphotericin b (10.57 - 13.63 mm inhibition zones). The AgNPs exhibited strong antioxidant activity in terms of nitric oxide scavenging (IC50 91.56 μg/mL), ABTS (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) radical scavenging (IC50 115.75 μg/mL), DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging (IC50 385.87 μg/mL), and reducing power (IC0.5 23.14 μg/mL). This study demonstrated the synthesis of spherical AgNPs with strong antibacterial, anticandidal and antioxidant properties that could potentially be utilised in the biomedical, cosmetic, food and pharmaceutical industries.
机译：本文研究了玉米（Zea mays L.）丝状毛发的水提物作为还原剂和稳定剂/加帽剂的绿色合成方法，该方法利用玉米的丝状毛发的水提物进行合成。通过紫外可见光谱，扫描电子显微镜（SEM），能量色散X射线分析（EDX），热重分析（TGA），X射线衍射（XRD）和傅立叶变换红外光谱（FT-IR）对AgNP进行表征。发现AgNP的平均尺寸为249.12nm。 AgNPs对五种不同的食源性致病细菌显示出强大的抗菌活性，抑制区的直径范围在（9.23-12.81 mm）之间。它还与标准抗生素，卡那霉素（10.6-13.65 mm抑制区）和利福平（10.02-12.86 mm抑制区）以及两性霉素b（10.57-13.63 mm抑制区）一起表现出有效的协同抗菌活性。 AgNPs在清除一氧化氮（IC50 91.56μg/ mL），ABTS（2,2'-叠氮基双（3-乙基苯并噻唑啉-6-磺酸）自由基清除（IC50 115.75μg/ mL）， DPPH（1,1-diphenyl-2-picrylhydrazyl）自由基清除（IC50 385.87μg/ mL）和还原能力（IC0.5 23.14μg/ mL）。这项研究证明了球形AgNPs的合成具有较强的抗菌，抗候选和抗氧化剂可能在生物医学，化妆品，食品和制药行业中使用的特性。

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