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Development of shampoo, soap and ointment formulated by green synthesised silver nanoparticles functionalised with antimicrobial plants oils in veterinary dermatology: treatment and prevention strategies

机译:在兽医皮肤病学中开发用抗菌植物油功能化的绿色合成银纳米颗粒配制的洗发水,肥皂和药膏:治疗和预防策略

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摘要

Many scientists have focused their research on the role of nanotechnology for the control of human pathogens, but there are also many topical pathogens present in animals, which infect animals and transfer to humans. Topical therapy is extremely important for the management of dermatological condition in animals. Therefore, the present study aims to evaluate the efficacy of biogenic silver nanoparticles (AgNPs) in combination with herbal oils against animal skin infections which may be responsible for causing infections in human beings. Here, the authors synthesised and characterised the AgNPs from The oils were extracted from medicinal plants including , and and the antifungal and antibacterial activity of plant oils along with AgNPs were evaluated. An excision wound model was used for the study of wound healing activity in rabbits. AgNPs functionalised oil has demonstrated remarkable antimicrobial activity against pathogens present on the skin of animals. The nano-functionalised antimicrobial oils were used in the formulation of shampoo, soap and ointment for veterinary dermatology. Antimicrobial products of plant origin with AgNPs are valuable, safe and have a specific role in controlling diseases. The authors believe that this approach will be a good alternative therapy to solve the continuous antibiotic resistance developed by many bacterial pathogens and will be utilised in various animal contacting areas in medicine.
机译:许多科学家将研究重点放在纳米技术对人类病原体控制的作用上,但动物中也存在许多局部病原体,它们会感染动物并转移给人类。局部治疗对于控制动物的皮肤病学状况极为重要。因此,本研究旨在评估生物银纳米颗粒(AgNPs)与草药油的结合对动物皮肤感染的功效,而动物皮肤感染可能是引起人类感染的原因。在这里,作者合成并鉴定了来自的植物油中的AgNP,并从中提取了药用油,并评估了植物油与AgNP的抗真菌和抗菌活性。切除伤口模型用于研究兔子的伤口愈合活性。 AgNPs功能化油对动物皮肤上存在的病原体具有显着的抗菌活性。纳米官能化的抗菌油用于兽医皮肤病的洗发水,肥皂和软膏剂配方中。具有AgNPs的植物来源的抗菌产品非常有价值,安全,并且在控制疾病方面具有特定作用。作者认为,这种方法将是解决许多细菌病原体产生的持续抗生素耐药性的良好替代疗法,并将在医学上与动物接触的各个领域得到利用。

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