• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Nanotechnology research journal >Nanotechnologies for Biomedical Metallic Materials
【24h】

Nanotechnologies for Biomedical Metallic Materials

机译：生物医学金属材料的纳米技术

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

An increasing demand for reliable metallic biomedical materials is being observed as a result of an ageing population with higher quality of life expectations. Improved metallic biomaterials and the relevant manufacturing techniques are being introduced to meet this demand. Apart from the biocompatibility requirement, metallic biomedical materials also have to meet high standards regarding its performance (functionality, reliability) and selection criteria (cost, manufacturing ability). Up to now, the most often used metallic biomedical materials include stainless steel, cobalt-based alloys and commercially pure titanium or titanium-based alloys. However, the implant metallic biomaterials, like all mechanical components, are subjected to degradation and have a limited lifetime. Damaged implants require a successive operation to replace worn components. Intensive efforts are made to increase durability of implants metallic biomaterials. Therefore, improved metallic biomaterials and the relevant manufacturing techniques are being introduced to meet this demand. Apart from the biocompatibility requirement, metallic biomedical materials also have to meet high standards regarding its performance (functionality, reliability) and selection criteria (cost, manufacturing ability). Up to now, the most often used metallic biomedical materials include stainless steel, cobalt-based alloys and commercially pure titanium or titanium-based alloys. However, the implant metallic biomaterials, like all mechanical components, are subjected to degradation and have limited lifetime. Damaged implant requires successive operation to replace worn components and so intensive efforts are made to increase durability of implants metallic biomaterials. For enhancing the mechanical retention, engineered nanostrucutres on the surface or bulk nanostructured materials are normally taken to increase effective area on implant surfaces (such as both dental and orthopedic applications) to exhibit biological, mechanical, and morphological compatibilities to receiving vital hard/soft tissue, resulting in promoting osseointegration. The engineered nanostructures play a crucial role in biomedical metallic materials because (ⅰ) the surface of a biomaterials is the only part contacting with the bioenvironment, (ⅱ) the surface region of a biomaterial is almost always different in morphology and composition from the bulk, (ⅲ) for biomaterials that do not release or leak biologically active or toxic substance, the characteristics of the surface governs the biological response (foreign material vs. host tissue), and (ⅳ) surface properties such as topography affect the mechanical stability of the implant-tissue interface. At the same time, implant industry is experiencing rapid growth mainly due to age-related degenerative diseases, with the increase of the need to diagnose diseases at an early stage in accordance with the saying: prevention is better than cure, the future prospects related to the significantly feasible nanostructured technology for the foreseeable future are also pointed out. It indicates that new bioengineering nanotechnologies should be explored to help the scientists and clinicians in the initiation of targeted treatments and in the follow up of treatment responses. Therefore, aim to provide vital information about the growing field of engineered nanostructures of the bulk metallic biomedical materials or on its surface, the nanotechnologies such as chemical/electrochemical action, mechanical indentations (sandblasting, shot peening, etc.), physical, chemical depositing techniques (PVD, CVD, plasma spraying, etc.), equal channel angular extrusion (ECAE), high pressure torsion (HPT), cold rolling, heat rolling, high energy ball milling, sand blasting and shot peening together with author's own results are reviewed.
机译：由于人口老龄化和更高的生活质量预期，对可靠的金属生物医学材料的需求正在增加。为了满足这种需求，正在引入改良的金属生物材料和相关的制造技术。除了生物相容性要求外，金属生物医学材料还必须满足有关其性能（功能，可靠性）和选择标准（成本，制造能力）的高标准。迄今为止，最常用的金属生物医学材料包括不锈钢，钴基合金和商业纯钛或钛基合金。然而，植入物金属生物材料，像所有机械部件一样，会发生降解，并且使用寿命有限。损坏的植入物需要连续操作以更换磨损的组件。为了增加植入物金属生物材料的耐用性，人们付出了巨大的努力。因此，正在引入改良的金属生物材料和相关的制造技术来满足该需求。除了生物相容性要求外，金属生物医学材料还必须满足有关其性能（功能，可靠性）和选择标准（成本，制造能力）的高标准。迄今为止，最常用的金属生物医学材料包括不锈钢，钴基合金和商业纯钛或钛基合金。然而，植入物金属生物材料，像所有机械部件一样，会降解并且寿命有限。损坏的植入物需要连续操作以更换磨损的组件，因此需要进行大量努力以提高植入物金属生物材料的耐用性。为了增强机械保持力，通常采用表面或大量纳米结构材料上的工程化纳米结构来增加植入物表面的有效面积（例如牙科和整形外科应用），以表现出生物，机械和形态相容性，以容纳重要的硬/软组织，从而促进骨整合。经过设计的纳米结构在生物医学金属材料中起着至关重要的作用，因为（ⅰ）生物材料的表面是与生物环境接触的唯一部分；（ⅱ）生物材料的表面区域在形态和组成上几乎总是与主体不同， （ⅲ）对于不会释放或泄漏生物活性或有毒物质的生物材料，其表面特性决定着生物反应（外来材料与宿主组织之间的关系），以及（ⅳ）表面特性（例如形貌）会影响其机械稳定性。植入物-组织界面。同时，由于年龄相关的退行性疾病，植入物行业正经历快速发展，这与俗语说的那样：尽早诊断疾病的需求越来越高：预防胜于治疗，未来的前景与还指出了在可预见的将来非常可行的纳米结构技术。这表明应该探索新的生物工程纳米技术，以帮助科学家和临床医生启动靶向治疗和后续治疗反应。因此，目标是提供有关重要的信息，这些信息涉及散装金属生物医学材料或其表面工程纳米结构的发展领域，化学/电化学作用，机械压痕（喷砂，喷丸处理等），物理，化学沉积等纳米技术。技术（PVD，CVD，等离子喷涂等），等通道角挤压（ECAE），高压扭转（HPT），冷轧，热轧，高能球磨，喷砂和喷丸以及作者自己的结果是已审查。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号