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首页> 外文期刊>Natural Product Research: Formerly Natural Product Letters >Chemical composition and antibacterial, antifungal and antioxidant activities of the flower oil of Retama raetam (Forssk.) Webb from Tunisia
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Chemical composition and antibacterial, antifungal and antioxidant activities of the flower oil of Retama raetam (Forssk.) Webb from Tunisia

机译:突尼斯的Retama raetam(Forssk。)Webb的花油的化学成分以及抗菌,抗真菌和抗氧化活性

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摘要

The chemical composition of the essential oils obtained by hydrodistillation from the flowers of Retama raetam (Forssk.) Webb cultivated in Tunisia was determined by GC and GC/MS analysis. A total of 50 components representing 98.58% of the oil were identified: nonanal (35.75%), α-humulene (29.29%), acetaldehyde (7.84%), linalool (5,62%), myrcene (3.38%), tridecanal (2.21%), β-caryophyllene (1.79%), α-terpinyl acetate (1.46%), terpinolene (1.26%) and methyl anthranilate (1.06%) were found to be the major components. The oil was evaluated for antibacterial and antifungal activities using a microdilution assay against some bacteria and yeasts. The minimal inhibitory concentrations (MIC) of the essential oil varied between 0.625 and 5 mg mL−1 and the minimum bactericidal concentrations (MBC) were superior to 5 mg mL−1 of oil for most strains. The antioxidant potential of the essential oil was evaluated using the 2,2′-diphenyl-1-picrylhydrazyl free radical scavenging method. The essential oil possesses good antioxidant properties (IC50 = 0.800 mg mL−1). The results may suggest that the flower oil of R. raetam possesses compounds with antibacterial, antifungal and antioxidant capacities, and thus the oil can be explored as a natural preservative ingredient in food and/or pharmaceutical preparations.
机译:通过GC和GC / MS分析测定通过水蒸馏从在突尼斯栽培的Retama raetam(Forssk。)Webb的花中获得的精油的化学组成。总共确定了占石油98.58%的50个成分:壬醛(35.75%),α--草烯(29.29%),乙醛(7.84%),芳樟醇(5,62%),月桂烯(3.38%),十三碳醛发现(2.21%),β-石竹烯(1.79%),α-乙酸叔丁酯(1.46%),萜品油烯(1.26%)和邻氨基苯甲酸甲酯(1.06%)是主要成分。使用针对某些细菌和酵母菌的微量稀释法评估了该油的抗菌和抗真菌活性。精油的最低抑菌浓度(MIC)在0.625至5 mg mL -1 之间变化,最低杀菌浓度(MBC)优于5 mg mL -1 对于大多数菌株来说都是油。香精油的抗氧化潜力使用2,2′-二苯基-1-吡啶并肼基自由基清除方法进行评估。该精油具有良好的抗氧化性能(IC 50 = 0.800 mg mL )。结果表明,R。raetam的花油具有具有抗菌,抗真菌和抗氧化能力的化合物,因此可以在食品和/或药物制剂中探索其为天然防腐剂的成分。

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    a Laboratoire des Maladies Transmissibles et des Substances Biologiquement Actives, Faculté de Pharmacie, Monastir, Tunisia b Laboratoire de Microbiologie CHU Fattouma Bourguiba, Monastir, Tunisia c USCR de Spectrométrie de Masse, Laboratoire de Biochimie, Faculté de Médecine, Monastir, Tunisia d Laboratoire de Chimie des Substances Naturelles et de Synthèse Organique, Faculté des Sciences de Monastir, Monastir, Tunisia;

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