The whole-genome landscape of medulloblastoma subtypes

著录项

• 来源
  《Nature》 |2017年第7663期|311-317|共7页
• 作者

  Northcott Paul A.; Buchhalter Ivo; Morrissy A. Sorana; Hovestadt Volker; Weischenfeldt Joachim; Ehrenberger Tobias; Groebner Susanne; Segura-Wang Maia; Zichner Thomas; Rudneva Vasilisa A.; Warnatz Hans-Joeg; Sidiropoulos Nikos; Phillips Aaron H.; Schumacher Steven; Kleinheinz Kortine; Waszak Sebastian M.; Erkek Serap; Jones David T. W.; Worst Barbara C. .; Kool Marcel; Zapatka Marc; Jaeger Natalie; Chavez Lukas; Hutter Barbara; Bieg Matthias; Paramasivam Nagarajan; Heinold Michael; Gu Zuguang; Ishaque Naveed; Jaeger-Schmidt Christina; Imbusch Charles D.; Jugold Alke; Huebschmann Daniel; Risch Thomas; Amstislavskiy Vyacheslav; Gonzalez Francisco German Rodriguez; Weber Ursula D.; Wolf Stephan; Robinson Giles W.; Zhou Xin; Wu Gang; Finkelstein David; Liu Yanling; Cavalli Florence M. G.; Luu Betty; Ramaswamy Vijay; Wu Xiaochong; Koster Jan; Ryzhova Marina; Cho Yoon-Jae; Pomeroy Scott L. .; Herold-Mende Christel; Schuhmann Martin; Ebinger Martin; Liau Linda M.; Mora Jaume; McLendon E.; Jabado Nada; Kumabe Toshihiro; Chuah Eric; Ma Yussanne; Moore Richard A.; Mungall Andrew J.; Mungall Karen L.; Thiessen Nina; Tse Kane; Wong Tina; Jones Steven J. M.; Witt Olaf; Milde Till; Von Deimling Andreas; Capper David; Korshunov Andrey; Yaspo Marie-Laure; Kriwacki Richard; Gajjar Amar; Zhang Jinghui; Beroukhim Rameen; Fraenkel Ernest; Korbel Jan O.; Brors Benedikt; Schlesner Matthias; Eils Roland; Marra Marco A.; Pfister Stefan M.; Taylor Michael D.; Lichter Peter;

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• 作者单位

  German Canc Res Ctr, Div Pediat Neurooncol, Heidelberg, Germany|St Jude Childrens Res Hosp, Dept Dev Neurobiol, 332 N Lauderdale St, Memphis, TN 38105 USA;

  German Canc Res Ctr, Div Theoret Bioinformat, Heidelberg, Germany|German Canc Res Ctr, Div Appl Bioinformat, Heidelberg, Germany|Heidelberg Univ, Inst Pharm & Mol Biotechnol IPMB & BioQuant, Dept Bioinformat & Funct Gen, Heidelberg, Germany;

  Hosp Sick Children, Dev & Stem Cell Biol Program, Toronto, ON, Canada;

  German Canc Res Ctr, Div Mol Genet, Heidelberg, Germany;

  Univ Copenhagen, BRIC, Copenhagen, Denmark|Finsen Lab, Rigshosp, Copenhagen, Denmark;

  MIT, Dept Biochem Engn, 77 Massachusetts Ave, Cambridge, MA 02139 USA;

  German Canc Res Ctr, Div Pediat Neurooncol, Heidelberg, Germany|German Canc Consortium DKTK, Heidelberg, Germany;

  EMBL, Genome Biol Unit, Heidelberg, Germany;

  EMBL, Genome Biol Unit, Heidelberg, Germany;

  St Jude Childrens Res Hosp, Dept Dev Neurobiol, 332 N Lauderdale St, Memphis, TN 38105 USA|EMBL, Genome Biol Unit, Heidelberg, Germany;

  Max Planck Inst Mol Genet, Dept Vertebrate Gen, Berlin, Germany;

  Univ Copenhagen, BRIC, Copenhagen, Denmark;

  St Jude Childrens Res Hosp, Dept Biol Struct, 332 N Lauderdale St, Memphis, TN 38105 USA;

  Broad Inst Harvard, Cambridge, MA USA|MIT, 77 Massachusetts Ave, Cambridge, MA 02139 USA;

  German Canc Res Ctr, Div Theoret Bioinformat, Heidelberg, Germany;

  EMBL, Genome Biol Unit, Heidelberg, Germany;

  German Canc Res Ctr, Div Pediat Neurooncol, Heidelberg, Germany|EMBL, Genome Biol Unit, Heidelberg, Germany;

  German Canc Res Ctr, Div Pediat Neurooncol, Heidelberg, Germany|German Canc Consortium DKTK, Heidelberg, Germany;

  German Canc Res Ctr, Div Pediat Neurooncol, Heidelberg, Germany|German Canc Consortium DKTK, Heidelberg, Germany;

  German Canc Res Ctr, Div Pediat Neurooncol, Heidelberg, Germany|German Canc Consortium DKTK, Heidelberg, Germany;

  German Canc Res Ctr, Div Mol Genet, Heidelberg, Germany;

  German Canc Res Ctr, Div Theoret Bioinformat, Heidelberg, Germany;

  German Canc Res Ctr, Div Pediat Neurooncol, Heidelberg, Germany|German Canc Consortium DKTK, Heidelberg, Germany;

  German Canc Res Ctr, Div Appl Bioinformat, Heidelberg, Germany;

  German Canc Res Ctr, Div Theoret Bioinformat, Heidelberg, Germany|German Canc Res Ctr, Heidelberg Ctr Personalized Oncol DKFZ HIPO, Heidelberg, Germany;

  German Canc Res Ctr, Div Theoret Bioinformat, Heidelberg, Germany|Heidelberg Univ, Med Fac Heidelberg, Heidelberg, Germany;

  German Canc Res Ctr, Div Theoret Bioinformat, Heidelberg, Germany|Heidelberg Univ, Inst Pharm & Mol Biotechnol IPMB & BioQuant, Dept Bioinformat & Funct Gen, Heidelberg, Germany;

  German Canc Res Ctr, Div Theoret Bioinformat, Heidelberg, Germany|German Canc Res Ctr, Heidelberg Ctr Personalized Oncol DKFZ HIPO, Heidelberg, Germany;

  German Canc Res Ctr, Div Theoret Bioinformat, Heidelberg, Germany|German Canc Res Ctr, Heidelberg Ctr Personalized Oncol DKFZ HIPO, Heidelberg, Germany;

  German Canc Res Ctr, Div Theoret Bioinformat, Heidelberg, Germany;

  German Canc Res Ctr, Div Appl Bioinformat, Heidelberg, Germany;

  German Canc Res Ctr, Div Theoret Bioinformat, Heidelberg, Germany;

  Heidelberg Univ, Inst Pharm & Mol Biotechnol IPMB & BioQuant, Dept Bioinformat & Funct Gen, Heidelberg, Germany|Heidelberg Hosp Univ, Dept Pediat Hematol & Oncol, Heidelberg, Germany;

  Max Planck Inst Mol Genet, Dept Vertebrate Gen, Berlin, Germany;

  Max Planck Inst Mol Genet, Dept Vertebrate Gen, Berlin, Germany;

  German Canc Res Ctr, Div Mol Genet, Heidelberg, Germany;

  Finsen Lab, Rigshosp, Copenhagen, Denmark|German Canc Res Ctr, Gen & Prote Core Facil, Heidelberg, Germany;

  St Jude Childrens Res Hosp, Dept Oncol, 332 N Lauderdale St, Memphis, TN 38105 USA;

  St Jude Childrens Res Hosp, Dept Computat Biol, 332 N Lauderdale St, Memphis, TN 38105 USA;

  St Jude Childrens Res Hosp, Dept Computat Biol, 332 N Lauderdale St, Memphis, TN 38105 USA;

  St Jude Childrens Res Hosp, Dept Computat Biol, 332 N Lauderdale St, Memphis, TN 38105 USA;

  St Jude Childrens Res Hosp, Dept Computat Biol, 332 N Lauderdale St, Memphis, TN 38105 USA;

  Hosp Sick Children, Dev & Stem Cell Biol Program, Toronto, ON, Canada;

  Hosp Sick Children, Dev & Stem Cell Biol Program, Toronto, ON, Canada;

  Hosp Sick Children, Dev & Stem Cell Biol Program, Toronto, ON, Canada;

  Hosp Sick Children, Dev & Stem Cell Biol Program, Toronto, ON, Canada;

  Amsterdam Med Ctr, Dept Oncogen, Amsterdam, Netherlands;

  NN Burdenko Inst Neurosurg, Dept Neuropathol, Moscow, Russia;

  Oregon Hlth & Sci Univ, Knight Canc Inst, Pape Family Pediat Res Inst, Dept Pediat, Portland, OR 97201 USA;

  Boston Childrens Hosp, Dept Neurol, Boston, MA USA|Harvard Med Sch, Boston, MA USA;

  Heidelberg Univ, Univ Clin, Heidelberg Hosp, Dept Neurosurg, Heidelberg, Germany;

  Univ Tubingen Hosp, Dept Neurosurg, Tubingen, Germany;

  Childrens Univ Hosp Tubingen, Dept Hematol & Oncol, Tubingen, Germany;

  Univ Calif Los Angeles, David Geffen Sch Med, Dept Neurosurg, Los Angeles, CA 90095 USA;

  Hosp San Juan Dios, Dev Tumor Biol Lab, Barcelona, Spain;

  Duke Univ, Dept Pathol, Durham, NC 27706 USA;

  McGill Univ, Dept Pediat, Montreal, PQ, Canada;

  Kitasato Univ, Sch Med, Dept Neurosurg, Sagamihara, Kanagawa, Japan;

  BC Canc Agcy, Michael Smith Genome Sci Ctr, Vancouver, BC, Canada;

  BC Canc Agcy, Michael Smith Genome Sci Ctr, Vancouver, BC, Canada;

  BC Canc Agcy, Michael Smith Genome Sci Ctr, Vancouver, BC, Canada;

  BC Canc Agcy, Michael Smith Genome Sci Ctr, Vancouver, BC, Canada;

  BC Canc Agcy, Michael Smith Genome Sci Ctr, Vancouver, BC, Canada;

  BC Canc Agcy, Michael Smith Genome Sci Ctr, Vancouver, BC, Canada;

  BC Canc Agcy, Michael Smith Genome Sci Ctr, Vancouver, BC, Canada;

  BC Canc Agcy, Michael Smith Genome Sci Ctr, Vancouver, BC, Canada;

  BC Canc Agcy, Michael Smith Genome Sci Ctr, Vancouver, BC, Canada;

  Heidelberg Hosp Univ, Dept Pediat Hematol & Oncol, Heidelberg, Germany;

  Heidelberg Hosp Univ, Dept Pediat Hematol & Oncol, Heidelberg, Germany;

  Univ Heidelberg Hosp, Dept Neuropathol, Heidelberg, Germany;

  Univ Heidelberg Hosp, Dept Neuropathol, Heidelberg, Germany;

  Univ Heidelberg Hosp, Dept Neuropathol, Heidelberg, Germany;

  Max Planck Inst Mol Genet, Dept Vertebrate Gen, Berlin, Germany;

  St Jude Childrens Res Hosp, Dept Biol Struct, 332 N Lauderdale St, Memphis, TN 38105 USA;

  St Jude Childrens Res Hosp, Dept Oncol, 332 N Lauderdale St, Memphis, TN 38105 USA;

  St Jude Childrens Res Hosp, Dept Computat Biol, 332 N Lauderdale St, Memphis, TN 38105 USA;

  Broad Inst Harvard, Cambridge, MA USA|MIT, 77 Massachusetts Ave, Cambridge, MA 02139 USA;

  MIT, Dept Biochem Engn, 77 Massachusetts Ave, Cambridge, MA 02139 USA;

  EMBL, Genome Biol Unit, Heidelberg, Germany;

  German Canc Res Ctr, Div Theoret Bioinformat, Heidelberg, Germany|German Canc Res Ctr, Div Appl Bioinformat, Heidelberg, Germany|German Canc Consortium DKTK, Heidelberg, Germany;

  German Canc Res Ctr, Div Theoret Bioinformat, Heidelberg, Germany;

  German Canc Res Ctr, Div Theoret Bioinformat, Heidelberg, Germany|Heidelberg Univ, Inst Pharm & Mol Biotechnol IPMB & BioQuant, Dept Bioinformat & Funct Gen, Heidelberg, Germany|German Canc Consortium DKTK, Heidelberg, Germany;

  BC Canc Agcy, Michael Smith Genome Sci Ctr, Vancouver, BC, Canada;

  German Canc Res Ctr, Div Pediat Neurooncol, Heidelberg, Germany|German Canc Consortium DKTK, Heidelberg, Germany|Heidelberg Hosp Univ, Dept Pediat Hematol & Oncol, Heidelberg, Germany;

  Hosp Sick Children, Dev & Stem Cell Biol Program, Toronto, ON, Canada|Hosp Sick Children, Div Neurosurg, Toronto, ON, Canada;

  German Canc Res Ctr, Div Mol Genet, Heidelberg, Germany|German Canc Consortium DKTK, Heidelberg, Germany;

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