Signals across domains of life

ERIC JAN

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Signals across domains of life

机译：跨越生活领域的信号

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All domains of life, from prokaryotes (archaea and bacteria) to eukaryotes (organisms that include plants, animals and fungi) use the ribosome apparatus to synthesize proteins by translating genetic code carried by messenger RNAs. Although the general steps of protein synthesis are evolutionarily conserved, the way in which ribo-somes are recruited to an mRNA molecule differs depending on the specific phylogenetic domain. In this issue, Colussi et al. (page 110) reveal the surprising finding that a eukaryotic ribosome-recruiting signal is functional in prokaryotic bacteria, thereby challenging the prevailing dogma that prokaryotic and eukaryotic ribosome recruitment are mutually exclusive.

机译：从原核生物（古细菌和细菌）到真核生物（包括植物，动物和真菌的生物）的所有生命领域都使用核糖体设备通过翻译信使RNA携带的遗传密码来合成蛋白质。尽管蛋白质合成的一般步骤在进化上是保守的，但核糖体募集到mRNA分子的方式因特定的系统发育域而异。在本期中，Collussi等。（第110页）揭示了令人惊讶的发现，即真核生物核糖体募集信号在原核细菌中起作用，从而挑战了流行的教条，即原核生物和真核生物核糖体募集是相互排斥的。

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《Nature》 |2015年第7541期|40-41|共2页
作者
ERIC JAN;
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Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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正文语种 eng
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Signals across domains of life

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