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Time to tackle cells' mistaken identity

机译:是时候解决细胞的错误身份了

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摘要

The differences between a cow and a monkey are clear. It is easy to tell a moth from a mosquito. So why are there still scientific studies that mix them up? The answer is simple: hundreds of cell lines stored and used by modern laboratories have been wrongly identified. Some pig cells are labelled as coming from a chicken; cell lines advertised as human have been shown to contain material from hamsters, rats, mice and monkeys. Which is worse: that such crude mix-ups exist, or that, every day, researchers use cell lines that somebody, somewhere has already found to be mislabelled, misidentified or contaminated? To solve the first problem is a huge challenge. To address the second is a more manageable task, and one that researchers, journals, universities and funders must take seriously.
机译:牛和猴子之间的区别很明显。很容易分辨出蚊子中的蛾子。那么为什么还有科学研究将它们混合在一起呢?答案很简单:现代实验室存储和使用的数百种细胞系被错误地鉴定出来。一些猪的细胞被标记为来自鸡。宣传为人类的细胞系已显示含有仓鼠,大鼠,小鼠和猴子的物质。哪一个更糟:存在这种粗略的混淆,或者每天,研究人员使用的细胞系中有人发现某个地方的标签或标识不正确或被污染了?解决第一个问题是巨大的挑战。解决第二个问题是一项更易于管理的任务,研究人员,期刊,大学和资助者必须认真对待这一任务。

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  • 来源
    《Nature》 |2015年第7547期|264-264|共1页
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  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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