Two disparate ligand-binding sites in the human P2Y_1 receptor

著录项

• 来源
  《Nature》 |2015年第7547期|317-321c3|共6页
• 作者

  Dandan Zhang; Zhan-Guo Gao; Kaihua Zhang; Evgeny Kiselev; Steven Crane; Jiang Wang; Silvia Paoletta; Cuiying Yi; Limin Ma; Wenru Zhang; Gye Won Han; Hong Liu; Vadim Cherezov; Vsevolod Katritch; Hualiang Jiang; Raymond C. Stevens; Kenneth A. Jacobson; Qiang Zhao; Beili Wu;

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• 作者单位

  CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Pudong, Shanghai 201203, China;

  Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA;

  CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Pudong, Shanghai 201203, China;

  Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA;

  Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA;

  CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Pudong, Shanghai 201203, China;

  Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA;

  CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Pudong, Shanghai 201203, China;

  CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Pudong, Shanghai 201203, China;

  CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Pudong, Shanghai 201203, China;

  Bridge Institute, Department of Chemistry, University of Southern California, Los Angeles, California 90089, USA;

  CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Pudong, Shanghai 201203, China;

  Bridge Institute, Department of Chemistry, University of Southern California, Los Angeles, California 90089, USA;

  Bridge Institute, Department of Biological Sciences, University of Southern California, Los Angeles, California 90089, USA;

  Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Pudong, Shanghai 201203, China;

  Bridge Institute, Department of Chemistry, University of Southern California, Los Angeles, California 90089, USA,Bridge Institute, Department of Biological Sciences, University of Southern California, Los Angeles, California 90089, USA,iHuman Institute, ShanghaiTech University, 99 Haike Road, Pudong, Shanghai 201203, China;

  Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA;

  CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Pudong, Shanghai 201203, China;

  CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Pudong, Shanghai 201203, China;

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