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A MOST EXCEPTIONAL RESPONSE

机译:最出色的反应

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摘要

If Patient X were like most people with advanced bladder cancer, she would probably be dead by now. After her first diagnosis, she received standard chemotherapy. It failed. Then she entered a clinical trial for a drug that was originally approved to treat other tumour types: would it also work in metastatic bladder cancer? Apparently not - none of the other patients in the trial did well. Yet Patient X thrived. Her tumour completely disappeared, says computational biologist Barry-Taylor at Memorial Sloan Kettering Cancer Center (MSKCC) in New York, where Patient X was treated. Today, a little more than five years after treatment, she is healthy and has no evidence of disease.
机译:如果X病人像大多数晚期膀胱癌患者一样,那么她现在可能已经死了。首次诊断后,她接受了标准化疗。失败了然后,她进入了一项针对最初被批准用于治疗其他肿瘤类型的药物的临床试验:该药物还可以用于转移性膀胱癌吗?显然不是-试验中的其他患者都没有表现良好。然而,X病人蓬勃发展。纽约纪念斯隆·凯特琳癌症中心(MSKCC)的计算生物学家Barry-Taylor说,她的肿瘤完全消失了。今天,在接受治疗大约五年后,她已经健康,没有疾病迹象。

著录项

  • 来源
    《Nature》 |2015年第7547期|389391-393|共4页
  • 作者

    VIVIEN MARX;

  • 作者单位
  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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  • 正文语种 eng
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