Natural killers take on cancer

Jacques Zimmer

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Natural killers take on cancer

机译：自然杀手患上癌症

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Your Outlook supplement on cancer immunotherapy (Nature 504, S1-S17; 2013) focuses mainly on T cells as a promising immunotherapy tool. But natural killer (NK) cells, another type of immune cell, may also be suitable for treatment of some cancers and are currently being tested in clinical trials (see, for example, A. M. James et al. Front. Immunol. 4,481; 2013, and M. Cheng et al. Cell. Mol. Immunol. 10,230-252; 2013).

机译：您对癌症免疫疗法的Outlook补充（Nature 504，S1-S17； 2013）主要关注T细胞作为一种有前途的免疫疗法工具。但是自然杀伤（NK）细胞（另一种类型的免疫细胞）也可能适合治疗某些癌症，目前正在临床试验中进行测试（参见，例如AM James等人，Front。Immunol。4,481； 2013，和M.Cheng等人，Cell.Mol.Immunol.10，230-252； 2013）。

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来源
《Nature》 |2014年第7484期|483-483|共1页
作者
Jacques Zimmer;
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Public Research Centre for Health, Luxembourg;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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1. Expansion of natural killer cells in patients with head and neck cancer: Detection of "noninhibitory" (activating) killer Ig-like receptors on circulating natural killer cells. [J] . Melioli G, Semino C, Margarino G, Head and neck: Journal for the sciences and specialities of the head and neck . 2003,第4期

机译：头颈部癌患者中自然杀伤细胞的扩增：循环自然杀伤细胞上“非抑制性”（激活）杀伤性Ig样受体的检测。
2. Anti-cancer activity of Angelica gigas by increasing immune response and stimulating natural killer and natural killer T cells [J] . Seo Hyun Kim, Sung Won Lee, Hyun Jung Park, BMC Complementary and Alternative Medicine . 2018,第1期

机译：通过提高免疫应答和刺激自然杀伤和自然杀伤T细胞来提高当归的抗癌活性
3. Hemacytotoxicity and natural killer lytic index: New parameters to evaluate, natural killer cell immunity for clinical use in cancer [J] . Maeng Hyung Gun, Lee Su Jin, Lee Yun A., Oncology letters . 2018,第1aPta2期

机译：血谱毒性和自然杀手裂变指数：评估的新参数，自然杀手细胞免疫癌症癌症
4. Quantification of low-affinity kinetics between cancer immunity relevant ligands and natural killer cell receptors with a self-induced back-action actuated nanopore electrophoresis (SANE) sensor [C] . George Alexandrakis, Sai Santosh Sasank Peri, Manoj Kumar Sabnani, Conference on Optical Trapping and Optical Micromanipulation . 2020

机译：用自诱导的背动作驱动纳米孔电泳（SANE）传感器的癌症免疫相关配体和天然杀伤细胞受体之间的低亲和力动力学的定量
5. Normalization of natural killer cell activity with effective antiretroviral therapy coincides with restoration of natural killer cell receptor expression [D] . Parato, Karl G. 2001

机译：用有效的抗逆转录病毒疗法使自然杀伤细胞活性正常化与恢复自然杀伤细胞受体表达相吻合
6. PD-1-positive Natural Killer Cells have a weaker antitumor function than that of PD-1-negative Natural Killer Cells in Lung Cancer [O] . Chao Niu, Min Li, Shan Zhu, 2020

机译：PD-1阳性天然杀伤细胞具有比肺癌中PD-1阴性自然杀伤细胞的抗肿瘤功能较弱
7. PD-1-positive Natural Killer Cells have a weaker antitumor function than that of PD-1-negative Natural Killer Cells in Lung Cancer [O] . Chao Niu, Min Li, Shan Zhu, 2020

机译：PD-1阳性天然杀伤细胞具有比肺癌中PD-1阴性自然杀伤细胞的抗肿瘤功能较弱

Natural killers take on cancer

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