In the social-media age, scientific disagreements can quickly become public - and vitriolic. A report from the ENCODE (Encyclopedia of DNA Elements) Project consortium proposes a framework for quantifying the functional parts of the human genome. It follows a controversial 2012 Nature paper by the same group that concluded that 80% of the genome is biochemically functional (Nature 489,57-74; 2012). Dan Graur, who studies molecular evolutionary bioinformatics at the University of Houston in Texas and is a vocal ENCODE critic, weighed in on this latest report. ENCODE s "stupid claims" from 2012 have finally come to back to "bite them in the proverbial junk", Graur wrote on his blog. The targets noticed.
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