Contamination hits cell work

EWEN CALLAWAY

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Contamination hits cell work

机译：污染影响细胞工作

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John Hogenesch saw the anguished look on his technician's face and knew instantly that her experiments had gone haywire; he also had a pretty good idea of why. "Check your culture for Mycoplasma contamination," he advised. The bacterium is notorious for infecting cell cultures, and had indeed compromised her experiments. In fact, the problem is widespread. Hogenesch, a genome biologist at the University of Pennsylvania in Philadelphia and his colleague Anthony Olarerin-George have found that more than one-tenth of gene-expression studies, many published in leading journals, show evidence of Mycoplasma contamination. The infestations are undermining research findings and wasting huge amounts of money, Hogenesch says.

机译：约翰·霍金施（John Hogenesch）看到了技术人员脸上的痛苦表情，立刻就知道自己的实验已经死了。他对为什么也有一个很好的主意。他建议：“检查您的培养物中是否存在支原体污染。”该细菌因感染细胞培养而臭名昭著，确实损害了她的实验。实际上，问题很普遍。费城宾夕法尼亚大学的基因组生物学家Hogenesch和他的同事Anthony Olarerin-George发现，超过十分之一的基因表达研究已显示出支原体污染的证据。霍金施说，这种侵扰正在破坏研究成果并浪费大量资金。

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《Nature》 |2014年第7511期|518-518|共1页
作者
EWEN CALLAWAY;
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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正文语种 eng
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1. Multivariate Calibration Approach for Quantitative Determination of Cell-Line Cross Contamination by Intact Cell Mass Spectrometry and Artificial Neural Networks [J] . Elisa Valletta, Luká? Ku?era, Lubomír Proke?, PLoS One . 2016,第1期

机译：完整细胞质谱和人工神经网络定量测定细胞系交叉污染的多元校正方法
2. Multivariate Calibration Approach for Quantitative Determination of Cell-Line Cross Contamination by Intact Cell Mass Spectrometry and Artificial Neural Networks [J] . Elisa Valletta, Luká? Ku?era, Lubomír Proke?, PLoS One . 2016,第1期

机译：完整细胞质谱和人工神经网络定量测定细胞系交叉污染的多元校正方法
3. On the Pilot Contamination Attack in Multi-Cell Multiuser Massive MIMO Networks [J] . Akbar Noman, Yan Shihao, Khattak Asad Masood, IEEE Transactions on Communications . 2020,第4期

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5. Polycistronic lentiviral vector for hit and run reprogramming of mouse and human somatic cells to induced pluripotent stem cell. [D] . Chang, Chia-Wei. 2009

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7. Contamination hits cell work [O] . Ewen Callaway 2014

机译：污染袭击了细胞工作
8. Calculation of dose and hit probability to cells irradiated in vitro by alpha particles. [R] . Hui, T. E., Brooks, A. L., Fisher, D. R., 1990

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Contamination hits cell work

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