Don't blame the mothers

Sarah S. Richardson

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Don't blame the mothers

机译：不要怪妈妈

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From folk medicine to popular culture, there is an abiding fascination with how the experiences of pregnant women imprint on their descendants. The latest wave in this discussion flows from studies of epigenetics-analyses of heritable changes to DNA that affect gene activity but not nucleotide sequence. Such DNA modification has been implicated in a child's future risk of obesity, diseases such as diabetes, and poor response to stress. Headlines in the press reveal how these findings are often simplified to focus on the maternal impact: 'Mother's diet during pregnancy alters baby's DNA' (BBC), 'Grandma's Experiences Leave a Mark on Your Genes' (Discover), and 'Pregnant 9/11 survivors transmitted trauma to their children' (The Guardian). Factors such as the paternal contribution, family life and social environment receive less attention.

机译：从民间医学到流行文化，人们一直对孕妇的经验如何在后代留下深刻的印象。本次讨论中的最新潮来自表观遗传学的研究-对影响基因活性但不影响核苷酸序列的DNA的遗传变化的分析。此类DNA修饰与儿童将来患肥胖症，疾病（例如糖尿病）和对压力的反应较差的风险有关。媒体上的头条新闻揭示了如何经常简化这些发现，以关注母体的影响：“怀孕期间母亲的饮食改变了婴儿的DNA”（BBC），“奶奶的经历在基因上留下了印记”（发现）和“ 9 / 11名幸存者向他们的孩子（《卫报》）传递了创伤。父亲的贡献，家庭生活和社会环境等因素受到的关注较少。

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来源
《Nature》 |2014年第7513期|131-132|共2页
作者
Sarah S. Richardson;
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作者单位

Harvard University in Cambridge, Massachusetts,USA;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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正文语种 eng
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Don't blame the mothers

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