Autism gene alters endocannibinoids

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Autism gene alters endocannibinoids

机译：自闭症基因改变内源性大麻素

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Certain gene mutations associated with autism interfere with nervous-system signals that activate the same pathways as cannabis. Some people with autism have a mutation or deletion in the neuronal gene neuroligin-3. But, although mice carrying a gene with the human mutation show autism-like behaviours, mice that lack the gene do not.

机译：与自闭症相关的某些基因突变会干扰神经系统信号，从而激活与大麻相同的途径。一些自闭症患者的神经元基因Neuroligin-3发生突变或缺失。但是，尽管携带带有人类突变基因的小鼠表现出自闭症般的行为，但缺少该基因的小鼠却没有。

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《Nature》 |2013年第7446期|400-401|共2页
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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1. Altered expression of glutamatergic and GABAergic genes in the valproic acid-induced rat model of autism: A screening test [J] . Toxicology: An International Journal Concerned with the Effects of Chemicals on Living Systems . 2020,第期

机译：改变谷胱甘肽和加布生物基因在丙丙酸诱导的自闭症大鼠大鼠模型中的表达：筛选试验
2. Excessive β-Catenin in Excitatory Neurons Results in Reduced Social and Increased Repetitive Behaviors and Altered Expression of Multiple Genes Linked to Human Autism [J] . Jonathan Michael Alexander, Antonella Pirone, Michele H. Jacob Frontiers in Synaptic Neuroscience . 2020,第2期

机译：兴奋性神经元中过量的β-catenin导致社会和重复行为增加，并改变了与人自闭症相关的多种基因的表达
3. Neural Response to Language in Toddlers with Autism Associated with Altered Gene Expression: Widespread and coordinated patterns of gene expression activity in leukocytes was linked to neural responses to speech across the brain [J] . American journal of medical genetics, Part A . 2019,第3期

机译：与改变基因表达相关的幼儿语言的神经响应：白细胞中基因表达活性的广泛和协调模式与脑穿过大脑的神经反应相关
4. Autism Gene: A visualization web platform of autism-related genes [C] . JIANG Dong-ke, GONG Sheng-tao, SUN Xiao 4th Chinese conference on bioinformatics and systems biology. . 2010

机译：自闭症基因：自闭症相关基因的可视化网络平台
5. Altered ultrasonic vocalizations in a tuberous sclerosis mouse model of autism. [D] . Young, David Matthew. 2010

机译：自闭症结节性硬化小鼠模型中超声发声的改变。
6. Excessive β-Catenin in Excitatory Neurons Results in Reduced Social and Increased Repetitive Behaviors and Altered Expression of Multiple Genes Linked to Human Autism [O] . Jonathan Michael Alexander, Antonella Pirone, Michele H. Jacob 2020

机译：兴奋性神经元中过多的β-连环素会导致社交行为和重复行为的减少以及与人类自闭症相关的多个基因的表达改变
7. Autism-associated SNPs in the clock genes _npas2_, _per1_ and the homeobox gene _en2_ alter DNA sequences that show characteristics of microRNA genes. [O] . Brad Nicholas, Michael J. Owen, Dawn C. Wimpory, 2008

机译：时钟基因_npas2 _，_ per1_和同源框基因_en2_中的自闭症相关SNP改变显示microRNA基因特征的DNA序列。

Autism gene alters endocannibinoids

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