The Lipinski rule of five

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The Lipinski rule of five

机译：利宾斯基五人制

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The medicinal chemist Christopher Lipinski and his colleagues analysed2 the physico-chemical properties of more than 2,000 drugs and candidate drugs in clinical trials, and concluded that a compound is more likely to be membrane permeable and easily absorbed by the body if it matches the following criteria:

机译：药物化学家Christopher Lipinski和他的同事在临床试验中分析了2千多种药物和候选药物的理化性质，并得出结论，如果化合物符合以下标准，则该化合物更可能具有膜渗透性并易于被人体吸收：

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《Nature》 |2012年第7382期|p.456|共1页
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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The Lipinski rule of five

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