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Brain scans need a rethink

机译:脑部扫描需要重新思考

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One of the most popular and widely accepted theories on the cause of autism spectrum disorders attributes the condition to disrupted connectivity between different regions of the brain. This connectivity hypothesis' claims that the social and cognitive abnormalities in people with autism can be explained by a dearth of connections between distant regions of the brain1. Some flavours of this theory also predict more connections between nearby brain regions.Recent studies, however, have found that when a person moves their head while undergoing functional magnetic resonance imaging (fMRI) - a method that maps how different neuroanatomical structures of the brain interact in real time, its functional connectivity - it looks like the neural activity observed in autism. That's a sobering discovery: it means that a major source of evidence for a leading hypothesis on autism, and one that several research teams have pursued for years, may arise from an artefact.
机译:关于自闭症谱系障碍原因的最流行和广泛接受的理论之一将这种状况归因于大脑不同区域之间的连接性破坏。这种连通性假说声称,自闭症患者的社交和认知异常可以用大脑较远区域之间缺乏联系来解释。该理论的某些特征还可以预测附近大脑区域之间的更多联系,但是最近的研究发现,当一个人在进行功能磁共振成像(fMRI)时移动其头部时-一种绘制大脑不同神经解剖结构相互作用方式的方法实时显示其功能连通性-就像自闭症中观察到的神经活动一样。这是一个发人深省的发现:这意味着人工制品可能是自闭症一种主要假说的主要证据来源,而一些研究团队多年来一直在寻求这种证据。

著录项

  • 来源
    《Nature》 |2012年第7422期|p.s20|共1页
  • 作者

    Ben Deen; Kevin Pelphrey;

  • 作者单位

    Massachusetts Institute of Technology in Cambridge;

    Child Study Center at Yale University in New Haven, Connecticut;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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