Understanding protein function: when less is more

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Understanding protein function: when less is more

机译：了解蛋白质功能：少即是多

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When someone figures out how to treat diseases related to the sarcoplasmic reticulum in muscle cells, such as Brody myopathy, Darier disease, and some forms of heart failure, they - and the patients who benefit - will need to thank Chikashi Toyoshima for his meticulous work at the University of Tokyo. In fact, his research on the calcium (Ca~(2+)) ion pump in these cells will also have biomedical and basic research beneficiaries in many other fields. The sarcoplasmic reticulum stores calcium ions that are released into muscle cells in response to electric stimulation of the muscle. These ions are pumped back by enzymes known as ATPases that power this cycle.

机译：当有人想出如何治疗与肌细胞的肌浆网有关的疾病（例如布罗迪肌病，Darier病和某些形式的心力衰竭）时，他们以及受益的患者将需要感谢Chikashi Toyoshima的精心工作在东京大学。实际上，他对这些细胞中的钙（Ca〜（2+））离子泵的研究也将在许多其他领域为生物医学和基础研究带来益处。肌浆网储存钙离子，该钙离子响应于肌肉的电刺激而释放到肌肉细胞中。这些离子被称为ATPase的酶泵回，该酶为该循环提供动力。

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《Nature》 |2011年第suppla期|p.34|共1页
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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6. Biases in the Experimental Annotations of Protein Function and Their Effect on Our Understanding of Protein Function Space [O] . Alexandra M. Schnoes, David C. Ream, Alexander W. Thorman, 2013

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7. Biases in the experimental annotations of protein function and their effect on our understanding of protein function space. [O] . Alexandra M Schnoes, David C Ream, Alexander W Thorman, 2013

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Understanding protein function: when less is more

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