Cyclin through drug resistance

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Cyclin through drug resistance

机译：细胞周期蛋白通过耐药

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Breast-cancer tumours can become resistant to therapy if they express abnormally high levels of the gene for a protein called cyclin E. The finding suggests that a combination of drugs targeted at specific molecules may one day be appropriate for such tumours. The therapeutic antibody trastuzumab is designed for breast cancers that overexpress the gene HER2, but patients frequently become resistant to the treatment.

机译：乳腺癌肿瘤如果表达异常高水平的称为细胞周期蛋白E的蛋白质的基因，就会对治疗产生抗药性。这一发现表明，针对特定分子的药物组合可能有一天适合此类肿瘤。治疗性抗体曲妥珠单抗设计用于过表达HER2基因的乳腺癌，但患者通常对治疗产生抗药性。

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《Nature》 |2011年第7335期|p.438|共1页
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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机译：质粒编码的抗性旋转分裂分裂型流动泵的出现赋予耐药性，包括替代药物，在<命名含量含量 - 型=“属型”> Klebsiella Pneumoniae 中
2. Drug Resistance of Staphylococci VII. Genetic Determinants Responsible for the Resistance to Tetracycline, Streptomycin, Sulfanilamide, and Penicillin [J] . Tokuhiko Kasuga, Hajime Hashimoto, Susumu Mitsuhashi Journal of bacteriology . 1968,第5期

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6. Emergence of a Plasmid-Encoded Resistance-Nodulation-Division Efflux Pump Conferring Resistance to Multiple Drugs Including Tigecycline in Klebsiella pneumoniae [O] . Luchao Lv, Miao Wan, Chengzhen Wang, 2020

机译：肺炎克雷伯氏菌中质粒编码的耐药结节外排泵的产生这些泵对多种药物（包括替加环素）具有耐药性
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Cyclin through drug resistance

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