Gene for malarial drug dodging

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Gene for malarial drug dodging

机译：疟疾药物躲避基因

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A genome-wide study of malaria parasites has revealed a novel gene that confers drug resistance. Pardis Sabeti at the Broad Institute in Cambridge, Massachusetts, and her team analysed 50 Plasmodium falciparum parasites from three continents and found 11 genes associated with resistance to antimalarial drugs. When they transferred one of these genes - which had not previously been associated with resistance - into parasites susceptible to drugs, the parasites became more resistant.

机译：疟疾寄生虫的全基因组研究揭示了赋予耐药性的新基因。马萨诸塞州剑桥市Broad研究所的Pardis Sabeti和她的团队分析了来自三大洲的50种恶性疟原虫，发现了11种与抗疟药耐药性相关的基因。当他们将这些基因之一（以前与抗药性没有关联）转移到对药物敏感的寄生虫中时，这些寄生虫就变得更具抗药性。

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《Nature》 |2011年第7346期|p.126|共1页
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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1. Drug repositioning as a route to anti-malarial drug discovery: preliminary investigation of the in vitro anti-malarial efficacy of emetine dihydrochloride hydrate [J] . Holly Matthews, Maryam Usman-Idris, Farid Khan, Malaria Journal . 2013,第S1期

机译：药物重新定位作为抗疟疾药物发现的途径：盐酸依米替丁二盐酸盐水合物的体外抗疟疾功效的初步研究
2. Drug repositioning as a route to anti-malarial drug discovery: preliminary investigation of the in vitro anti-malarial efficacy of emetine dihydrochloride hydrate [J] . Holly Matthews, Maryam Usman-Idris, Farid Khan, Malaria Journal . 2013,第S1期

机译：药物重新定位作为抗疟疾药物发现的途径：盐酸依米替丁二盐酸盐水合物的体外抗疟疾功效的初步研究
3. Does anti-malarial drug knowledge predict anti-malarial dispensing practice in drug outlets? A survey of medicine retailers in western Kenya [J] . Andria Rusk, Nathan Smith, Diana Menya, Malaria Journal . 2012,第S1期

机译：抗疟疾药物知识是否可以预测药物出口的抗疟疾配药实践？肯尼亚西部药品零售商的调查
4. Novel inhibitor-based photoaffinity labeling and MALDI mass spectrometry for identification of anti-malarial drug targets [C] . David Wood, Michael Prinsen, Megh Singh, ASMS Conference on Mass Spectrometry and Allied Topics . 2015

机译：基于新型抑制剂的光化亚蜜位标记和MALDI质谱法，用于鉴定抗疟疾药物靶标
5. Drug price control policy and access to malarial drugs in India [D] . Mohapatra, Debi Prasad. 2016

机译：印度的药品价格控制政策和获取疟疾药品的途径
6. Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor artemisinic acid [O] . Dae-Kyun Ro, Mario Ouellet, Eric M Paradise, 2008

机译：在酵母中诱导多个多效性耐药基因以产生更高水平的抗疟药前体青蒿酸
7. Gene for malarial drug dodging [O] . 2011

机译：疟疾药物躲避的基因

Gene for malarial drug dodging

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