Hidden diversity sparks adaptation

JEREMY A. DRAGHI; JOSHUA B. PLOTKIN

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Hidden diversity sparks adaptation

机译：隐藏的多样性激发适应

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Is genetic variation primarily neutral, or is it predominantly shaped by natural selection? Biologists have debated this question for decades. And although the neutralist-selectionist argument has fuelled advances in our understanding of molecular evolution, it has contributed less to our knowledge of how organisms adapt to changing environments. Recent theories about robustness and evolv-ability, as well as experiments with enzymes and with microbes, suggest that adaptation may depend on a deep and largely unappreciated interaction between neutral and beneficial mutations. On page 92 of this issue, Hayden et al.~1 describe an empirical test of this hypothesis.

机译：遗传变异主要是中性的，还是主要由自然选择塑造？几十年来，生物学家一直在争论这个问题。尽管中立选择主义者的论点促进了我们对分子进化的理解，但对我们对生物体如何适应不断变化的环境的认识却贡献不大。关于健壮性和进化能力的最新理论，以及酶和微生物的实验表明，适应性可能取决于中性和有益突变之间的深层相互作用，而很大程度上是未被认识的相互作用。在本期杂志的第92页上，Hayden等人〜1描述了该假设的实证检验。

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《Nature》 |2011年第7349期|p.45-46|共2页
作者
JEREMY A. DRAGHI; JOSHUA B. PLOTKIN;
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作者单位

Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA;

Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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1. Adaptation of hidden Markov model for telephone speech recognition and speaker adaptation [J] . Chien J.-T., Wang H.-C. IEE Proceedings. Part K . 1997,第3期

机译：隐马尔可夫模型的自适应用于语音识别和说话人自适应
2. Adaptation of hidden Markov model for telephone speech recognition and speaker adaptation [J] . J.-T Chien, H .-C. Wang IEE Proceedings. Part K . 1997,第3期

机译：隐马尔可夫模型的自适应用于语音识别和说话人自适应
3. Species Pool Functional Diversity Plays a Hidden Role in Generating -Diversity [J] . Patrick Christopher J., Brown Bryan L. The American Naturalist: Devoted to the Conceptual Unification of the Biological Sciences . 2018,第5期

机译：物种池功能多样性在生成的大学中起着隐藏的作用
4. Adaptation of Classical Machine Learning Algorithms to Big Data Context: Problems and Challenges : Case Study: Hidden Markov Models Under Spark [C] . Imad SASSI, Sara OUAFTOUH, Samir ANTER International Conference on Smart Systems and Data Science . 2019

机译：经典机器学习算法对大数据上下文的适应：问题与挑战：案例研究：Spark下的隐马尔可夫模型
5. The hidden spark of Hasidism in Martin Buber's philosophy of dialogue. [D] . Taylor, John. 2009

机译：Hasidism在马丁·布伯对话哲学中的隐藏火花。
6. Diversity in a hidden world: potential and limitation of next-generation sequencing for surveys of molecular diversity of eukaryotic microorganisms [O] . RALPH MEDINGER, VIOLA NOLTE, RAM VINAY PANDEY, -1

机译：隐藏世界中的多样性：对真核微生物的分子多样性调查的下一代测序的潜力和限制
7. Poetry and sound: the hidden meaning: a cognitive approach to meaningful sound patterns in works by Marlowe, Hopkins, Williams, Spark and Heaney = Sonido y poesía: el signicado escondido: Un acercamiento cognitivo a estructuras de sonido significativas en poemas de Marlowe, Hopkins, Williams, Spark y Heaney [O] . Galetti Torti Edgardo 2010

机译：诗歌和声音：隐藏的含义：马洛，霍普金斯，威廉姆斯，斯帕克和希尼的作品中有意义的声音模式的认知方法= Sonido ypoesía：声音的象征：声音的建构，Marlowe的声音构成，霍普金斯，威廉姆斯，Spark y Heaney

Hidden diversity sparks adaptation

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