Getting past a brain block

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Getting past a brain block

机译：克服大脑障碍

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A physiological defence mechanism called the blood-brain barrier prevents toxins from entering the brain, but it also blocks molecules such as drugs and fluorescent dyes. Tara Spires-Jones at the Massachusetts General Hospital in Charlestown and her colleagues circumvented this problem by coating molecules with carbohydrate nanoparticles.

机译：一种称为血脑屏障的生理防御机制可以防止毒素进入大脑，但它也可以阻止药物和荧光染料等分子。查尔斯敦马萨诸塞州综合医院的塔拉·斯皮雷斯·琼斯（Tara Spires-Jones）和她的同事们用碳水化合物纳米颗粒包被分子，从而解决了这个问题。

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《Nature》 |2011年第7373期|p.271|共1页
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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1. In response to the letter to the editor: Beta blockers therapy in traumatic brain injury: Is it the time to disclose the brain-cardiac interactions? [J] . Ley Eric J., Dhillon Navpreet K., Barmparas Galinos The journal of trauma and acute care surgery . 2019,第2期

机译：为了回应编辑的信：β受体阻滞剂在创伤性脑损伤中疗法：是时候披露脑心脏互动的时间？
2. Beta blockers therapy in traumatic brain injury: Is it the time to disclose the brain-cardiac interactions? [J] . El-Menyar Ayman The journal of trauma and acute care surgery . 2018,第3期

机译：β受体阻滞剂治疗创伤性脑损伤：是时候披露脑心脏互动的时间？
3. Pyruvate blocks blood-brain barrier disruption, lymphocyte infiltration and immune response in excitotoxic brain injury [J] . Jae K Ryu, James G McLarnon American Journal of Neurodegenerative Disease . 2016,第1期

机译：丙酮酸阻断兴奋性脑损伤中的血脑屏障破坏，淋巴细胞浸润和免疫反应
4. Blocking NMDA Mediated DYN Neurotoxicity Influences Brain Lipids Profile in Traumatic Brain Injury. [C] . Amina S. Woods, Shelley N Jackson, Aurelie Roux, ASMS Conference on Mass Spectrometry and Allied Topics . 2015

机译：阻断NMDA介导的DYN神经毒性会影响创伤性脑损伤中的脑脂质谱。
5. Blocking Brain Tumor Necrosis Factor to Alleviate Persistent Inflammatory Pain [D] . Mustafa, Sibtain. 2020

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6. Transcriptomic Analysis of Mouse Brain After Traumatic Brain Injury Reveals That the Angiotensin Receptor Blocker Candesartan Acts Through Novel Pathways [O] . Peter J. Attilio, Dustin M. Snapper, Milan Rusnak, 2021

机译：创伤性脑损伤后小鼠脑的转录组分分析表明血管紧张素受体阻滞剂坎德坦通过新颖的途径作用
7. Arginine-Vasopressin Receptor Blocker Conivaptan Reduces Brain Edema and Blood-Brain Barrier Disruption after Experimental Stroke in Mice. [O] . Emil Zeynalov, Susan M Jones, Jeong-Woo Seo, 2015

机译：精氨酸加压素受体阻滞剂Conivaptan可减轻小鼠实验性卒中后脑水肿和血脑屏障的破坏。

Getting past a brain block

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