Noise rules

HANA EL-SAMAD; JONATHAN S. WEISSMAN

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Noise rules

机译：噪音规则

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Ever since Gregor Mendel and Thomas Morgan crystallized the idea of the gene as the heritable unit, biologists have been trying to map the relationship between genotype (the complement of gene variants present in an individual) and phenotype (an individual's physical characteristics). On page 250 of this issue, Lehner and colleagues1 provide insight into the complexity of this relationship by showing how random variation in the expression of members of pairs of interacting genes can act synergistically to affect the development of a complex organism - the roundworm Caenorhabditis elegans.

机译：自从Gregor Mendel和Thomas Morgan将基因的概念明确化为可遗传单位以来，生物学家一直在尝试绘制基因型（个体中存在的基因变异的互补物）与表型（个体的身体特征）之间的关系。在此问题的第250页上，Lehner及其同事1通过显示相互作用基因对成员的表达中的随机变化如何协同作用来影响复杂生物-round虫秀丽隐杆线虫的发育，从而深入了解了这种关系。

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来源
《Nature》 |2011年第7376期|p.188-189|共2页
作者
HANA EL-SAMAD; JONATHAN S. WEISSMAN;
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作者单位

Department of Biochemistry and Biophysics University of California, San Francisco, San Francisco, California 94158, USA;

Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, California 94158, USA;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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正文语种 eng
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Noise rules

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