Mapping intact protein isoforms in discovery mode using top-down proteomics

著录项

• 来源
  《Nature》 |2011年第7376期|p.254-258|共5页
• 作者

  John C. Tran; Leonid Zamdborg; Dorothy R. Ahlf; Ji Eun Lee; Adam D. Catherman; Kenneth R. Durbin; Jeremiah D. Tipton; Adaikkalam Vellaichamy; John F. Kellie; Mingxi Li; Cong Wu; Steve M. M. Sweet; Bryan P. Early; Nertila Siuti; Richard D. LeDuc; Philip D. Compton; Paul M. Thomas; Neil L. Kelleher;

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• 作者单位

  Departments of Chemistry and Biochemistry, and the Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA,Departments of Chemistry and Molecular Biosciences and the Feinberg School of Medicine, Northwestern University, Evanston, Illinois 60208, USA;

  Departments of Chemistry and Biochemistry, and the Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA;

  Departments of Chemistry and Biochemistry, and the Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA,Departments of Chemistry and Molecular Biosciences and the Feinberg School of Medicine, Northwestern University, Evanston, Illinois 60208, USA;

  Departments of Chemistry and Biochemistry, and the Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA,Doping Control Center and Center for Theragnosis, Korea Institute of Science and Technology, Seoul, South Korea;

  Departments of Chemistry and Biochemistry, and the Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA,Departments of Chemistry and Molecular Biosciences and the Feinberg School of Medicine, Northwestern University, Evanston, Illinois 60208, USA;

  Departments of Chemistry and Biochemistry, and the Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA,Departments of Chemistry and Molecular Biosciences and the Feinberg School of Medicine, Northwestern University, Evanston, Illinois 60208, USA;

  Departments of Chemistry and Molecular Biosciences and the Feinberg School of Medicine, Northwestern University, Evanston, Illinois 60208, USA;

  Departments of Chemistry and Biochemistry, and the Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA,Department of Nanomedicine, The Methodist Hospital Research Institute, Houston, Texas 77030, USA (A.V.) Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA (N.S.);

  Departments of Chemistry and Biochemistry, and the Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA,Departments of Chemistry and Molecular Biosciences and the Feinberg School of Medicine, Northwestern University, Evanston, Illinois 60208, USA;

  Departments of Chemistry and Biochemistry, and the Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA,Departments of Chemistry and Molecular Biosciences and the Feinberg School of Medicine, Northwestern University, Evanston, Illinois 60208, USA;

  Departments of Chemistry and Biochemistry, and the Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA;

  Departments of Chemistry and Biochemistry, and the Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA,Departments of Chemistry and Molecular Biosciences and the Feinberg School of Medicine, Northwestern University, Evanston, Illinois 60208, USA;

  Departments of Chemistry and Biochemistry, and the Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA,Departments of Chemistry and Molecular Biosciences and the Feinberg School of Medicine, Northwestern University, Evanston, Illinois 60208, USA;

  Departments of Chemistry and Biochemistry, and the Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA,Department of Nanomedicine, The Methodist Hospital Research Institute, Houston, Texas 77030, USA (A.V.) Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA (N.S.);

  Department of Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA;

  Departments of Chemistry and Molecular Biosciences and the Feinberg School of Medicine, Northwestern University, Evanston, Illinois 60208, USA;

  Departments of Chemistry and Biochemistry, and the Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA,Departments of Chemistry and Molecular Biosciences and the Feinberg School of Medicine, Northwestern University, Evanston, Illinois 60208, USA;

  Departments of Chemistry and Biochemistry, and the Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA,Departments of Chemistry and Molecular Biosciences and the Feinberg School of Medicine, Northwestern University, Evanston, Illinois 60208, USA;

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