BOX 1 Established immune treatments

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BOX 1 Established immune treatments

机译：方框1建立了免疫治疗

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Nine monoclonal antibodies targeting six cancer-associated proteins (Her2eu, EGFR, VEGF, CD20, CD52 and CD33) are approved for the treatment of solid and haematological malignancies. In addition to antagonizing oncogenic pathways, these biotherapeutics may act by opsonizing tumour cells and triggering their death or removal by antibody-dependent cellular cytotoxity or phagocytosis94. Ongoing investigations in murine models and patients raise the possibility that they may also stimulate adaptive immune responses in some settings~(95).

机译：九种针对六种癌症相关蛋白（Her2 / neu，EGFR，VEGF，CD20，CD52和CD33）的单克隆抗体被批准用于治疗实体和血液恶性肿瘤。除了拮抗致癌途径外，这些生物疗法还可能通过调理肿瘤细胞并通过抗体依赖性细胞的细胞毒作用或吞噬作用触发其死亡或清除94。正在进行的对鼠模型和患者的研究增加了他们在某些情况下也可能刺激适应性免疫反应的可能性[95]。

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《Nature》 |2011年第7378期|p.480|共1页
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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1. ERβ-Dependent Direct Suppression of Human and Murine Th17 Cells and Treatment of Established Central Nervous System Autoimmunity by a Neurosteroid [J] . Maria Aggelakopoulou, Evangelia Kourepini, Nikolaos Paschalidis, The journal of immunology . 2016,第7期

机译：ERβ依赖的人类和小鼠Th17细胞的直接抑制和神经类固醇的已建立的中枢神经系统自身免疫性治疗
2. ER beta-Dependent Direct Suppression of Human and Murine Th17 Cells and Treatment of Established Central Nervous System Autoimmunity by a Neurosteroid [J] . Aggelakopoulou Maria, Kourepini Evangelia, Paschalidis Nikolaos, The Journal of Immunology: Official Journal of the American Association of Immunologists . 2016,第7期

机译：ER beta依赖性人类和小鼠Th17细胞的直接抑制和神经类固醇的已建立的中枢神经系统自身免疫性治疗
3. Update on Rituximab: An Established Treatment for All Immune-Mediated Kidney Diseases? [J] . Rhys Evans, Alan D. Salama Nephron . 2014,第3期

机译：利妥昔单抗的最新进展：所有免疫介导的肾脏疾病的既定治疗方法？
4. COMPARISON OF COLD WIND BOX AND HOT WIND BOX OPERATIONS OF AN RCFB INCINERATION SYSTEM FOR THE TREATMENT OF DISTILLERY SPENT WASH [C] . Babu J. Alappat, Vishwanath C. Rane International Conference on Fluidized Bed Combustion . 1995

机译：冷风箱和热风箱的比较RCFB焚烧系统治疗酿酒厂
5. Establishing an immune gene signature for stage II cutaneous melanoma at high risk of recurrence. [D] . Sivendran, Shanthi. 2011

机译：为高复发风险的II期皮肤黑素瘤建立免疫基因标记。
6. Immune-related response evaluations during immune-checkpoint inhibitor therapy: establishing a common language for the new arena of cancer treatment [O] . Mizuki Nishino 2016

机译：免疫检查点抑制剂治疗期间的免疫相关反应评估：为癌症治疗的新领域建立通用语言
7. Immune-related response evaluations during immune-checkpoint inhibitor therapy: establishing a “common language” for the new arena of cancer treatment [O] . 2016

机译：免疫检查点抑制剂治疗期间的免疫相关反应评估：为癌症治疗的新领域建立“通用语言”

BOX 1 Established immune treatments

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