Small RNAs are on the move

Daniel H. Chitwood; Marja C. P. Timmermans

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Small RNAs are on the move

机译：小型RNA在移动

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A key feature of RNA interference is its ability to spread from cell to cell. Such non-cell-autonomous gene silencing has been characterized extensively in both plants and animals, but the identity of the mobile silencing signal has remained elusive. Several recent studies now shed light on the identity of this signal in plants, and indicate that small RNA molecules-from short-interfering RNAs to microRNAs-are capable of moving between cells and through the vasculature. The movement of small, 21-24-nucleotide RNA species has implications for biological processes ranging from developmental patterning and stress responses to epigenetic inheritance.

机译：RNA干扰的关键特征是其在细胞之间扩散的能力。这种非细胞自主基因沉默已在植物和动物中得到广泛表征，但移动沉默信号的身份仍然难以捉摸。现在，一些最新研究揭示了植物中该信号的身份，并表明小RNA分子（从短干扰RNA到微RNA）可以在细胞之间移动并通过脉管系统。 21-24个核苷酸的小RNA物种的移动对生物学过程具有影响，这些生物学过程涉及从发育模式和应激反应到表观遗传的过程。

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来源
《Nature》 |2010年第7314期|P.415-419|共5页
作者
Daniel H. Chitwood; Marja C. P. Timmermans;
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作者单位

Section of Plant Biology, University of California at Davis, Davis, California 95616, USA;

rnCold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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正文语种 eng
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2. miRNAs on the move: miRNA biogenesis and the RNAi machinery. [J] . Murchison EP, Hannon GJ Current Opinion in Cell Biology . 2004,第3期

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4. The Move to Alternatives [C] . Claas Rostock German Shipowner's Association;Motorship Propulsion and Future Fuels Conference . 2019

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5. Connecting Genre-Based and Corpus-Driven Approaches in Research Articles: A Comparative Study of Moves and Lexical Bundles in Saudi and International Journals. [D] . Alamri, Basim M. 2017

机译：在研究文章中连接基于体裁和语料库驱动的方法：沙特和国际期刊中的举动和词汇捆绑的比较研究。
6. Conundrum of the Lack of Defective RNAs (dRNAs) Associated with Tobamovirus Infections: dRNAs That Can Move Are Not Replicated by the Wild-Type Virus; dRNAs That Are Replicated by the Wild-Type Virus Do Not Move [O] . Elisabeth Knapp, William O. Dawson, Dennis J. Lewandowski 2001

机译：缺乏与烟草花叶病毒感染相关的缺陷性RNA（dRNA）的难题：可以移动的dRNA不会被野生型病毒复制。由野生型病毒复制的dRNA不会移动
7. Conundrum of the Lack of Defective RNAs (dRNAs) Associated with Tobamovirus Infections: dRNAs That Can Move Are Not Replicated by the Wild-Type Virus; dRNAs That Are Replicated by the Wild-Type Virus Do Not Move† [O] . Knapp, Elisabeth, Dawson, William O., Lewandowski, Dennis J. 2001

机译：缺乏与烟草花叶病毒感染相关的缺陷性RNA（dRNA）的难题：可以移动的dRNA不会被野生型病毒复制。由野生型病毒复制的dRNA不会移动†

Small RNAs are on the move

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