SEVEN DAYS

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SEVEN DAYS

机译：七天

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Global investment in commercial research and development (R&D) by the world s biggest research spenders dropped by just 1.9% in 2009, according to the European Union's annual investment Scoreboard, released on 26 October. That ends four consecutive years of growth in R&D, but the 1,400 companies in the survey experienced, on average, a 10.1% drop in sales and a 21 % fall in profits in 2009. See go.nature.com/mv63xe for more.

机译：根据10月26日发布的欧盟年度投资记分牌，全球最大的研究机构在全球的商业研究与开发（R＆D）投资在2009年仅下降了1.9％。这结束了连续四年的研发增长，但接受调查的1400家公司在2009年的平均销售额下降了10.1％，利润下降了21％。有关更多信息，请访问go.nature.com/mv63xe。

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《Nature》 |2010年第7320期|p.10-11|共2页
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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1. Elderly multiple myeloma (MM) patients, who are generally ineligible for transplantation, have high risks of death and treatment discontinuation, and require a regimen incorporating novel agents that balance safety, tolerability, and efficacy. We evaluated alternating bortezomib-dexamethasone and lenalidomide-dexamethasone treatments administered over a 63-day cycle in transplant-ineligible elderly patients with newly diagnosed MM. Subcutaneous bortezomib 1.3 mg/m2 was administered weekly on Days 1, 8, 15, and 22; oral lenalidomide 15 mg daily on Days 36-56; and oral dexamethasone 20 mg on Days 1, 8, 15, 22, 36, 43, 50, and 57 for 6 cycles. The primary endpoint was the overall response rate. [J] . Yokoyama Akihiro, Kada Akiko, Saito Akiko M., Acta medica Okayama . 2019,第6期

机译：通常不适合移植的老年多发性骨髓瘤（MM）患者具有很高的死亡和中止治疗的风险，因此需要一种方案，该方案应采用能够平衡安全性，耐受性和疗效的新型药物。我们评估了在不适合移植的老年初诊MM患者中，硼替佐米-地塞米松和来那度胺-地塞米松在63天周期内的交替治疗。在第1、8、15和22天每周一次皮下注射硼替佐米1.3 mg / m2;在第36-56天每天口服来那度胺15 mg;在第1、8、15、22、36、43、50和57天，口服地塞米松20 mg，共6个周期。主要终点是总体缓解率。
2. Same-Day Versus Next-Day Discharge Increased Pain on the Day After, But Not on the Day of or Four Weeks After, Total Hip Arthroplasty [J] . Vail Thomas Parker The Journal of Bone and Joint Surgery. American Volume . 2017,第4期

机译：当天与下一天的当天与一天的痛苦增加，但不在一天或四周之后，总髋关节置换术
3. Randomized Phase II Study of Guadecitabine (SGI-110) Based Regimens Comparing Guadecitabine 5 days (SGI5), 10 days (SGI10), 5 days + Idarubicin (SGI5 + Ida), and 5 days + Cladribine (SGI5 + Clad), in Previously Untreated Patients ≥ 70 Years with Acute Myeloid Leukemia (AML)–a Bayesian Design [J] . Kiran Naqvi, Garciela Nogueras Gonzalez, Cora Cheung, Clinical lymphoma, myeloma & leukemia . 2017,第10期

机译：基于瓜鹃（SGI-110）的随机阶段II研究比较瓜鹃阿硝滨5天（SGI5），10天（SGI10），5天+偶霉素（SGI5 + IDA）和5天+ Cladribine（SGI5 + Clad），在前一种方案未经治疗的患者≥70岁，急性髓性白血病（AML）-A贝叶斯设计
4. Day-to-day and within-day network dynamics encapsulating hyperbolic traffic behavior [C] . Hsun-Jung Cho, Ming-Chorng Hwang, Hsien-Hung Shih . 2004

机译：每日和每日的网络动态封装了双曲线的流量行为
5. Measuring outcomes: The impact of a three-day mental health training on juvenile corrections officers day-to-day decision -making regarding the mentally ill youth in their care. [D] . Kroening, Kathleen M. 2002

机译：评估结果：为期三天的心理健康培训对青少年矫正人员在他们所护理的精神病患者中进行日常决策的影响。
6. Efficacy of 7-Day and 14-Day Bismuth-Containing Quadruple Therapy and 7-Day and 14-Day Moxifloxacin-Based Triple Therapy as Second-Line Eradication for Helicobacter pylori Infection [O] . Seong tae Lee, Dong Ho Lee, Ji Hyun Lim, 2019

机译：7天和14天含铋四联疗法和7天和14天莫西沙星为基础的三联疗法根除幽门螺杆菌感染的疗效
7. Table 3: Above: Fire Weather Index system code and index values for the 25th, 50th and 90th percentiles for control days/combined fire and control days (‘all’ days); Below: difference between the fire day percentile and the control/all day percentile and for (A) all fire days and (B) large fire days. [O] . -1

机译：表3：以上：控制天/组合火灾和控制天的25，50和第90百分位数的火灾天气指数系统代码和索引值（'所有'天）;以下：火日百分位数与控制/全天百分比之间的差异和（a）所有火灾日和（b）大火日。

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