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Travelling-wave Nuclear Magnetic Resonance

机译:行波核磁共振

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Nuclear magnetic resonance (NMR) is one of the most versatile experimental methods in chemistry, physics and biology, providing insight into the structure and dynamics of matter at the molecular scale. Its imaging variant-magnetic resonance imaging (MRI)-is widely used to examine the anatomy, physiology and metabolism of the human body. NMR signal detection is traditionally based on Faraday induction in one or multiple radio-frequency resonators that are brought into close proximity with the sample. Alternative principles involving structured-material flux guides, superconducting quantum interference devices, atomic magnetometers, Hall probes or magnetoresis-tive elements have been explored. However, a common feature of all NMR implementations until now is that they rely on close coupling between the detector and the object under investigation. Here we show that NMR can also be excited and detected by long-range interaction, relying on travelling radio-frequency waves sent and received by an antenna. One benefit of this approach is more uniform coverage of samples that are larger than the wavelength of the NMR signal-an important current issue in MRI of humans at very high magnetic fields. By allowing a significant distance between the probe and the sample, travelling-wave interaction also introduces new possibilities in the design of NMR experiments and systems.
机译:核磁共振(NMR)是化学,物理和生物学中用途最广泛的实验方法之一,可洞察分子规模上物质的结构和动力学。它的成像变异磁共振成像(MRI)-被广泛用于检查人体的解剖结构,生理和新陈代谢。 NMR信号检测传统上是基于一个或多个与样品非常接近的射频谐振器中的法拉第感应。已经探索了涉及结构材料通量导管,超导量子干涉装置,原子磁力计,霍尔探头或磁阻元件的替代原理。但是,到目前为止,所有NMR实施的共同特征是它们依赖检测器与被调查物体之间的紧密耦合。在这里,我们证明了NMR也可以依靠天线发送和接收的行进射频波,通过长距离相互作用来激发和检测。这种方法的一个好处是,比NMR信号波长更大的样本覆盖范围更均匀-这是在非常高的磁场下人MRI中的一个重要的当前问题。通过在探针和样品之间留出较大的距离,行波相互作用还为NMR实验和系统的设计带来了新的可能性。

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