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Heating Up Labs Everywhere

机译:到处加热实验室

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摘要

Just as the universe is constantly expanding, so is the universe of laboratory products and tools. In the galaxy of laboratory equipment, here are a few of the hottest stars that could fuel your research and produce higher quality data. Interest in RNA has skyrocketed due to its role as a gene silencer and potential target for therapeutic drugs. However, RNA samples are difficult to work with given their labile nature and tendency to degrade, even in cold storage. Biomatrica's RNAstableTM uses a unique stabilization technology that protects RNA samples from degradation during long-term storage or transport. To store RNA, researchers simply pipette their samples into a tube or well of RNAstable and let it dry. RNA is preserved at room temperature for up to 10 months and has demonstrated an equivalent of 5.5 years stability under accelerated aging conditions. RNAstable is better at preventing degradation than freezer storage, thus increasing experimental reproducibility and reliability. Sample recovery is easy-just add water and the sample can then be used directly in downstream applications such as quantitative real time-PCR, bioanalyzer and microarray analysis, cDNA synthesis and reverse transcription.
机译:就像宇宙在不断扩展一样,实验室产品和工具的宇宙也在不断扩大。在实验室设备星系中,有一些最热门的恒星可能会助您一臂之力,并产生更高质量的数据。由于其作为基因沉默剂和治疗药物的潜在靶点,对RNA的兴趣激增。然而,鉴于RNA样品的不稳定性质和降解趋势,即使在冷藏中,也很难对其进行处理。 Biomatrica的RNAstableTM使用独特的稳定技术,可保护RNA样品在长期存储或运输过程中不被降解。要存储RNA,研究人员只需将样品吸移到RNAstable试管或孔中,使其干燥即可。 RNA在室温下可以保存长达10个月,并且在加速老化条件下已证明相当于5.5年的稳定性。 RNAstable在防止降解方面比在冰箱中更好,从而提高了实验的可重复性和可靠性。样品回收很容易,只需加水即可将样品直接用于下游应用,例如定量实时PCR,生物分析仪和微阵列分析,cDNA合成和逆转录。

著录项

  • 来源
    《Nature》 |2008年第7204期|p.iii|共2页
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  • 作者单位
  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 自然科学总论;
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