Alzheimer's tests under fire

Erika Check Hayden

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Alzheimer's tests under fire

机译：阿尔茨海默氏症的测试

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Genetic testing for Alzheimer's disease tells a cautionary tale about the legal, medical and ethical complications of personal genomics, as the story of a Pennsylvania company shows. Smart Genetics, based in Philadelphia, has stopped offering its controversial 'Alzheimer's Mirror' genetic test just eight months after introducing it. The test checked for variants in a gene, called APOE, that bestow as much as a 15-fold increased risk of developing Alzheimer's. Soon after launching the test, though, Smart Genetics chief executive Julian Awad found himself in a controversy over whether it violated intellectual-property agreements covering APOE testing.

机译：宾夕法尼亚州一家公司的故事显示，阿尔茨海默氏病的基因检测讲述了有关个人基因组学在法律，医学和道德方面的并发症的警示性故事。引入费城的Smart Genetics公司在推出有争议的“阿尔茨海默氏镜”基因测试后仅八个月就停止提供它。该测试检查了称为APOE的基因中的变异，这种变异可使患阿尔茨海默氏症的风险增加了15倍。但是，在启动测试后不久，Smart Genetics首席执行官朱利安·阿瓦德（Julian Awad）就是否违反了涉及APOE测试的知识产权协议而陷入争议。

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《Nature》 |2008年第7217期|p.1155|共1页
作者
Erika Check Hayden;
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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Alzheimer's tests under fire

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