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Molecular motion pictures

机译:分子电影

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摘要

Molecules in solution change their conformations so quickly that no method has been able to record the process. This looks set to change, as infrared spectroscopy rises to the challenge. The science of high-speed photography was created by Eadweard Muybridge in 1887, when he published his famous photographic sequence of a galloping racehorse. Scientists have since sought analogous microscopic and spectroscopic techniques to enable them to watch the motion of biological molecules in real time. As reported on page 469 of this issue, Hamm and co-workers have transferred the principles of high-speed photography to two-dimensional infrared spectroscopy. In this way, events that occur over a few hundred picoseconds can be studied by taking a series of snapshots — that is, two-dimensional infrared spectra — of the molecules concerned.
机译:溶液中的分子如此迅速地改变其构象,以致没有方法能够记录该过程。随着红外光谱技术的挑战,这一情况似乎将改变。高速摄影科学是由埃德韦德·穆布里奇(Eadweard Muybridge)于1887年发明的,当时他发表了著名的奔腾赛马摄影作品。此后,科学家一直在寻求类似的显微和光谱技术,以使他们能够实时观察生物分子的运动。正如本期第469页所报道的那样,Hamm和他的同事们已经将高速摄影的原理转移到了二维红外光谱学上。这样,可以通过拍摄有关分子的一系列快照(即二维红外光谱)来研究发生在几百皮秒内的事件。

著录项

  • 来源
    《Nature》 |2006年第7118期|p.431-432|共2页
  • 作者

    Minhaeng Cho;

  • 作者单位
  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 自然科学总论;
  • 关键词

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