• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Nature >Sustained firing in auditory cortex evoked by preferred stimuli
【24h】

Sustained firing in auditory cortex evoked by preferred stimuli

机译：持续刺激激发听觉皮层

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

It has been well documented that neurons in the auditory cortex of anaesthetized animals generally display transient responses to acoustic stimulation, and typically respond to a brief stimulus with one or fewer action potentials(1-5). The number of action potentials evoked by each stimulus usually does not increase with increasing stimulus duration(1,5-7). Such observations have long puzzled researchers across disciplines and raised serious questions regarding the role of the auditory cortex in encoding ongoing acoustic signals. Contrary to these long-held views, here we show that single neurons in both primary ( area A1) and lateral belt areas of the auditory cortex of awake marmoset monkeys ( Callithrix jacchus) are capable of firing in a sustained manner over a prolonged period of time, especially when they are driven by their preferred stimuli. In contrast, responses become more transient or phasic when auditory cortex neurons respond to non-preferred stimuli. These findings suggest that when the auditory cortex is stimulated by a sound, a particular population of neurons fire maximally throughout the duration of the sound. Responses of other, less optimally driven neurons fade away quickly after stimulus onset. This results in a selective representation of the sound across both neuronal population and time.
机译：已有文献证明，麻醉动物的听觉皮层中的神经元通常会表现出对声刺激的短暂反应，并且通常会对短暂的刺激产生一个或更少的动作电位（1-5）。每个刺激引起的动作电位数量通常不会随着刺激持续时间的增加而增加（1,5-7）。这种观察长期以来一直困扰着各个学科的研究人员，并提出了有关听觉皮层在编码持续的声信号中的作用的严重问题。与这些长期存在的观点相反，在这里我们显示清醒的mo猴（Callithrix jacchus）的听觉皮层的初级（A1区）和外侧带区域中的单个神经元能够持续持续发射时间，尤其是当它们受到其偏好刺激的驱动时。相反，当听觉皮层神经元对非优选刺激作出反应时，反应变得更加短暂或阶段性。这些发现表明，当声音刺激听觉皮层时，特定的神经元群体会在整个声音持续时间内最大程度地发射。刺激开始后，其他非最佳驱动神经元的反应迅速消失。这导致跨神经元群体和时间的声音的选择性表示。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号