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The ring of life provides evidence for a genome fusion origin of eukaryotes

机译:生命之环为真核生物的基因组融合起源提供了证据

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Genomes hold within them the record of the evolution of life on Earth. But genome fusions and horizontal gene transfer seem to have obscured sufficiently the gene sequence record such that it is difficult to reconstruct the phylogenetic tree of life. Here we determine the general outline of the tree using complete genome data from representative prokaryotes and eukaryotes and a new genome analysis method that makes it possible to reconstruct ancient genome fusions and phylogenetic trees. Our analyses indicate that the eukaryotic genome resulted from a fusion of two diverse prokaryotic genomes, and therefore at the deepest levels linking prokaryotes and eukaryotes, the tree of life is actually a ring of life. One fusion partner branches from deep within an ancient photosynthetic clade, and the other is related to the archaeal prokaryotes. The eubacterial organism is either a proteobacterium, or a member of a larger photosynthetic clade that includes the Cyanobacteria and the Proteobacteria.
机译:基因组中保存着地球生命进化的记录。但是基因组融合和水平基因转移似乎已经充分掩盖了基因序列记录,从而难以重建系统发育树。在这里,我们使用来自有代表性的原核生物和真核生物的完整基因组数据以及一种新的基因组分析方法来确定树的总体轮廓,该新的基因组分析方法使重建古代基因组融合和系统发育树成为可能。我们的分析表明,真核基因组是两个不同原核基因组融合而成的,因此,在将原核生物和真核生物联系在一起的最深层次上,生命之树实际上就是生命之环。一个融合伴侣从一个古老的光合进化枝中分支出来,另一个与古细菌原核生物有关。真细菌生物是变形杆菌,或者是包括蓝细菌和变形细菌在内的较大的光合进化枝的成员。

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