Detection of preinvasive cancer cells

V. Backman; M. B. Wallace; L. T. Perelman; J. T. Arendt; R. Gurjar; M. G. Mueller; Q. Zhang; G. Zonios; E. Kline; T. McGillican; S. Shapshay; T. Valdez; K. Badizadegan; J. M. Crawford; M. Fitzmaurice; S. Kabani; H. S. Levin

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Detection of preinvasive cancer cells

机译：浸润前癌细胞的检测

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More than 85% of all cancers originate in the epithelium that lines the internal surfaces of organs throughout the body. Although these are readily treatable provided they are diagnosed in one of the preinvasive stages, early lesions are often almost impossible to detect. Here we present a new optical-probe technique based on light-scattering spectroscopy that is able to detect precancerous and early cancerous changes in cell-rich epithelia.

机译：在所有癌症中，超过85％的起源于上皮细胞，该上皮细胞遍布整个器官的内表面。尽管只要在浸润前阶段之一中对其进行诊断即可轻松治疗，但通常几乎无法检测到早期病变。在这里，我们提出了一种基于光散射光谱的新型光学探针技术，该技术能够检测富含细胞的上皮细胞的癌前期和早期癌变。

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《Nature》 |2000年第6791期|p.35-36|共2页
作者
V. Backman; M. B. Wallace; L. T. Perelman; J. T. Arendt; R. Gurjar; M. G. Mueller; Q. Zhang; G. Zonios; E. Kline; T. McGillican; S. Shapshay; T. Valdez; K. Badizadegan; J. M. Crawford; M. Fitzmaurice; S. Kabani; H. S. Levin;
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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正文语种 eng
中图分类自然科学总论;
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1. Single-cell transcriptomes of pancreatic preinvasive lesions and cancer reveal acinar metaplastic cells’ heterogeneity [J] . Yehuda Schlesinger, Oshri Yosefov-Levi, Dror Kolodkin-Gal, Nature Communications . 2020,第1期

机译：胰腺预筛病变和癌症的单细胞转录om显示癌母细胞的异质性
2. DCLK1 marks a morphologically distinct subpopulation of cells with stem cell properties in preinvasive pancreatic cancer [J] . BaileyJ.M., AlsinaJ., RasheedZ.A., Gastroenterology . 2014,第1期

机译：DCLK1标志着在浸润前胰腺癌中具有干细胞特性的细胞形态上独特的亚群
3. Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse. [J] . Hingorani SR, Petricoin EF, Maitra A, Cancer Cell . 2003,第6期

机译：浸润前和浸润性导管胰腺癌及其在小鼠中的早期检测。
4. Cancer detection using an electronic nose: A preliminary study on detection and discrimination of cancerous cells [C] . Thriumani R., Zakaria A., Jeffree A.I., 2014 IEEE Conference on Biomedical Engineering and Sciences . 2014

机译：使用电子鼻进行癌症检测：检测和区分癌细胞的初步研究
5. Integration of copy number aberration and genomic expression data in preinvasive breast cancer [D] . Perry, Victoria Kristina 2012

机译：浸润前乳腺癌中拷贝数畸变和基因组表达数据的整合
6. β-Catenin determines upper airway progenitor cell fate and preinvasive squamous lung cancer progression by modulating epithelial–mesenchymal transition [O] . Adam Giangreco, Liwen Lu, Charles Vickers, -1

机译：β-连环蛋白通过调节上皮-间质转化确定上呼吸道祖细胞命运和浸润前鳞状上皮癌的进展
7. DCLK1 Marks a Morphologically Distinct Subpopulation of Cells With Stem Cell Properties in Preinvasive Pancreatic Cancer [O] . Plentz, Ruben 2014

机译：DCLK1标志着在浸润前胰腺癌中具有干细胞特性的细胞在形态上不同的亚群。
8. Molecular Detection of Circulating Cancer Cells for Early Diagnosis of Breast Cancer [R] . Reinholz, M. M. , Roche, P. C. 2002

机译：循环癌细胞的分子检测在乳腺癌早期诊断中的应用

Detection of preinvasive cancer cells

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