CRISPR-BASEDGENE THERAPY DAMPENS PAIN IN MICE

Remmel Ariana

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CRISPR-BASEDGENE THERAPY DAMPENS PAIN IN MICE

机译：CRISPR-CASISINGGENE治疗抑制小鼠的疼痛

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Targeted approach could lead to an opioid-free way of treating chronic pain.CRISPR-based gene therapy dampens pain in mice Targeted approach could lead to an opioid-free way of treating chronic pain.

机译：有针对性的方法可能导致治疗慢性疼痛的无阿片类药物。基于基于的基因治疗抑制患者靶向方法的抑制疼痛可能导致治疗慢性疼痛的阿片类药物。

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来源
《Nature》 |2021年第7850期|359-359|共1页
作者
Remmel Ariana;
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作者单位

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类
关键词
Sensory systems; Neuroscience; CRISPR-Cas9 genome editing;

机译：感官系统;神经科学;CRISPR-CAS9基因组编辑;

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专利

1. Diurnal amplitudes of arterial pressure and heart rate are dampened in Clock mutant mice and adrenalectomized mice. [J] . Sei H, Oishi K, Chikahisa S, Endocrinology . 2008,第7期

机译：在Clock突变小鼠和肾上腺切除小鼠中，动脉压和心率的昼夜振幅被衰减。
2. Macrophage Toll-like Receptor 9 Contributes to Chemotherapy-Induced Neuropathic Pain in Male Mice [J] . Luo Xin, Huh Yul, Bang Sangsu, The Journal of Neuroscience: The Official Journal of the Society for Neuroscience . 2019,第35期

机译：巨噬细胞般的受体9有助于在雄性小鼠中进行化疗诱导的神经性疼痛
3. Putative Role of Ethanolic Extract of Vernonia cinerea in the Amelioration of Chemotherapy Induced Neuropathic Pain in Mice [J] . Srikanta Chandra, Avik Das, Jyotirmay Samanta, Journal of Drug Delivery and Therapeutics . 2019,第3as期

机译：灰霉病菌的乙醇提取物在改善化疗引起的小鼠神经性疼痛中的作用
4. Combination of nitric oxide therapy, anti-oxidative therapy, low level laser therapy, plasma rich platelet therapy and stem cell therapy as a novel therapeutic application to manage the pain and treat many clinical conditions [C] . Salaheldin Halasa, Eva Dickinson Mechanisms for low-light therapy IX . 2014

机译：一氧化氮治疗，抗氧化治疗，低水平激光治疗，富含血浆的血小板治疗和干细胞治疗相结合，是一种新颖的治疗疼痛和多种临床疾病的治疗方法
5. Fullerene carbon-70 derivatives dampen anaphylaxis and allergic asthma pathogenesis in mice. [D] . Norton, Sarah Brooke. 2012

机译：富勒烯碳70衍生物可抑制小鼠的过敏反应和过敏性哮喘发病机理。
6. Tumor-targeted hybrid protein oxygen carrier to simultaneously enhance hypoxia-dampened chemotherapy and photodynamic therapy at a single dose [O] . Zhenyu Luo, Hao Tian, Lanlan Liu, 2018

机译：以肿瘤为靶点的混合蛋白氧载体以单剂量同时增强缺氧抑制的化学疗法和光动力疗法
7. Sodium channel NaV1.9 mutations associated with insensitivity to pain dampen neuronal excitability [O] . Jianying Huang, Carlos G. Vanoye, Alison Cutts, 2017

机译：钠通道Nav1.9与疼痛抑制神经元兴奋性的不敏感相关的突变

CRISPR-BASEDGENE THERAPY DAMPENS PAIN IN MICE

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