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The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.

机译：嗜热菌Aquifex aeolicus的完整基因组。

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Aquifex aeolicus was one of the earliest diverging, and is one of the most thermophilic, bacteria known. It can grow on hydrogen, oxygen, carbon dioxide, and mineral salts. The complex metabolic machinery needed for A. aeolicus to function as a chemolithoautotroph (an organism which uses an inorganic carbon source for biosynthesis and an inorganic chemical energy source) is encoded within a genome that is only one-third the size of the E. coli genome. Metabolic flexibility seems to be reduced as a result of the limited genome size. The use of oxygen (albeit at very low concentrations) as an electron acceptor is allowed by the presence of a complex respiratory apparatus. Although this organism grows at 95 degrees C, the extreme thermal limit of the Bacteria, only a few specific indications of thermophily are apparent from the genome. Here we describe the complete genome sequence of 1,551,335 base pairs of this evolutionarily and physiologically interesting organism.
机译：Aquifex aeolicus是最早的发散之一，也是已知的最嗜热的细菌之一。它可以在氢气，氧气，二氧化碳和无机盐上生长。基因组仅编码大肠杆菌所需的复杂的代谢机制，使其成为化学自养生物（一种使用无机碳源进行生物合成和使用无机化学能源的生物）。基因组。由于基因组大小的限制，新陈代谢的灵活性似乎有所降低。复杂的呼吸装置的存在允许使用氧气（尽管浓度很低）作为电子受体。尽管该生物体在95摄氏度（细菌的极端温度极限）下生长，但从基因组中仅发现了几个嗜热菌病的具体迹象。在这里，我们描述了这种进化上和生理上有趣的有机体的1,551,335个碱基对的完整基因组序列。

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