Max's modelling

Martin Kemp

首页> 外文期刊>Nature >Max's modelling

【24h】

Max's modelling

机译：马克斯的造型

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

When Linus Pauling and Roger Hayward called their 1964 book The Architecture of Molecules they were resorting to an age-old style of metaphorical allusion. As knowledge of molecular structure has entered worlds that are impossible to 'see' in any normal sense, analogies with objects in our normal range of visual experience have lost none of their efficacy as aids to visualization. One of the most spectacular acts of modelling was initiated in 1937 by Max Perutz's work on haemoglobin. As Perutz graphically recalled, "the first protein structures revealed wonderful new faces of nature". That he found it necessary to reveal these "faces" visually rather than mathematically became rapidly apparent: "I began giving a course in X-ray crystallography of biologically important molecules for students of biochemistry and other biomedical subjects. In my first lecture I introduced lattice theory, trigonometric functions, and Fourier series... but half the students failed to turn up for my second lecture.... The following year I replaced my forbidding lecture with a non-mathematical, largely pictorial introduction called 'Diffraction Without Tears'."

机译：当莱纳斯·鲍林（Linus Pauling）和罗杰·海沃德（Roger Hayward）在1964年出版的《分子的体系结构》一书时，他们诉诸了一种古老的隐喻性典范。由于分子结构的知识已经进入了从任何正常意义上都无法“看到”的世界，因此与我们正常的视觉体验范围内的物体进行类比并不会失去其作为可视化辅助工具的功效。麦克斯·佩鲁兹（Max Perutz）在血红蛋白方面的工作始于1937年，是最壮观的建模动作之一。正如佩鲁茨（Graphertz）用图形表示的那样，“第一个蛋白质结构揭示了自然界的奇妙新面孔”。他发现有必要从视觉上而不是从数学上迅速显现出这些“面孔”：“我开始为生物化学和其他生物医学专业的学生开设有关生物学重要分子的X射线晶体学课程。在我的第一堂课中，我介绍了晶格理论，三角函数和傅立叶级数...但是有一半的学生没有参加我的第二堂课....第二年，我用一种非数学的，基本上是图形的介绍代替了我那令人讨厌的讲座，称为“没有眼泪的衍射” 。”

著录项

来源
《Nature》 |1998年第6683期|p.315|共1页
作者
Martin Kemp;
展开▼
作者单位

展开▼
收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
关键词

相似文献

外文文献
中文文献
专利

1. Max Kuhn and Kjell Johnson . Applied Predictive Modeling . New York , Springer . Max Kuhn Max Max Kuhn Kuhn and Kjell Johnson Kjell Kjell Johnson Johnson . Applied Predictive Modeling Applied Predictive Modeling . New York New York , Springer Springer . [J] . Rizopoulos Dimitris Biometrics: Journal of the Biometric Society : An International Society Devoted to the Mathematical and Statistical Aspects of Biology . 2018,第1期

机译：Max Kuhn和Kjell Johnson。应用预测建模。纽约，斯普林克。 Max Kuhn Max Max Kuhn Kuhn和Kjell Johnson Kjell Kjell Johnson Johnson。应用预测建模应用预测建模。纽约纽约，斯普林克斯普林克。
2. Expectation-Maximization-Maximization: A Feasible MLE Algorithm for the Three-Parameter Logistic Model Based on a Mixture Modeling Reformulation [J] . Chanjin Zheng, Xiangbin Meng, Shaoyang Guo, Frontiers in Psychology . 2017,第4期

机译：期望最大化最大化：基于混合建模重构的三参数Logistic模型可行的MLE算法
3. Estimation and prediction with ARMMAX model: a mixture of ARMAX models with common ARX part [J] . Li He, Miroslav Karny International Journal of Adaptive Control and Signal Processing . 2003,第4期

机译：使用ARMMAX模型进行估计和预测：ARMAX模型与常见ARX部件的混合
4. Maximum Likelihood Parameter Estimation for ARMAX Models Based on Stochastic Gradient Algorithm [C] . Lun Li, Yan Pu, Jing Chen International Conference on Modelling, Identification and Control . 2018

机译：基于随机梯度算法的ARMAX模型最大似然参数估计
5. A Mathematical Model for Predicting Maximal Heart Rate, Maximal Oxygen Uptake, and Oxygen Uptake Kinetics During Walking and Running at Varied Intensities [D] . Borror, Andrew Maurice. 2018

机译：在不同强度的步行和跑步过程中预测最大心率，最大摄氧量和摄氧动力学的数学模型
6. Expectation-Maximization-Maximization: A Feasible MLE Algorithm for the Three-Parameter Logistic Model Based on a Mixture Modeling Reformulation [O] . Chanjin Zheng, Xiangbin Meng, Shaoyang Guo, -1

机译：期望最大化最大化：基于混合建模重构的三参数Logistic模型可行的MLE算法
7. Caracterização da curva do lactato sanguíneo e aplicabilidade do modelo Dmax durante protocolo progressivo em esteira rolante La caracterización de la curva del lactato sanguíneo y la pertinencia del Dmax durante el protocolo progresivo en la cinta rodante Characterization of the blood lactate curve and applicability of the Dmax model in a progressive protocol on treadmill [O] . Flávio de Oliveira Pires, Adriano Eduardo Lima Silva, João Fernando Laurito Gagliardi, 2006

机译：渐进式跑步机方案期间血乳酸曲线的表征和Dmax模型的适用性在滚动带协议期间表征血乳酸曲线和Dmax的相关性血乳酸曲线的表征在跑步机上的渐进式协议
8. Ada Compiler Validation Summary Report. Certificate Number: 910130W1.11114,Encore Computer Corporation Parallel Ada Development System, Revision 1.0, Encore 91 Series (Model no. 91-0340) under UMAX 3.0 => Encore 91 Series (Model No. 91-0340) under UMAX 3. [R] . 1991

机译：ada编译器验证摘要报告。证书编号：910130W1.11114，Encore计算机公司平行ada开发系统，1.0版，Encore 91系列（型号91-0340），UmaX 3.0下的Encore 91系列（型号91-0340）。

Max's modelling

摘要

著录项

相似文献

相关主题

期刊订阅