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ACTIVATION OF MEDIAL TEMPORAL STRUCTURES DURING EPISODIC MEMORY RETRIEVAL

机译：回忆记忆中的中间时间结构的激活

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MEDIAL temporal lobe structures have been implicated in human episodic memory. Patients with medial temporal lesions show memory deficits(1-3), and functional neuroimaging studies have revealed activation in this region during episodic encoding and retrieval when data are averaged over a sample of subjects(4-7). The relevance of such observations for memory performance has remained unclear, however. Here we have used positron emission tomography (PET) to examine cerebral blood how related to verbal episodic retrieval. We observed strong positive correlations between retrieval and blood flow in left medial temporal structures in individual normal human subjects. In addition, multivariate analysis showed that regions in the left medial temporal lobe were dominant components of a pattern of brain regions that distinguished a high-retrieval condition from conditions of lower retrieval. These results suggest that medial temporal activity is related to retrieval success rather than retrieval attempt, possibly by reflecting reactivation of stored patterns. [References: 25]
机译：内侧颞叶结构已经牵涉到人类的情节记忆中。颞部内侧病变的患者显示记忆力减退（1-3），而功能性神经影像学研究发现，当对受试者样本进行平均数据时，在间歇性编码和检索过程中该区域被激活（4-7）。但是，这种观察与记忆性能的相关性还不清楚。在这里，我们使用正电子发射断层扫描（PET）来检查脑血与言语情节检索之间的关系。我们观察到个体正常个体的左侧内侧颞叶结构中的取血与血流之间存在强正相关。此外，多变量分析表明，左颞颞叶中的区域是大脑区域模式的主要组成部分，该区域将高检索条件与低检索条件区分开。这些结果表明，内侧颞部活动与检索成功而不是检索尝试有关，可能是通过反映存储模式的重新激活来实现的。 [参考：25]

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