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INFANT LEUKAEMIA AFTER IN UTERO EXPOSURE TO RADIATION FROM CHERNOBYL

机译：切尔诺贝利辐射引起的子宫内暴露后婴儿白血病

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THERE has been no documented increase in childhood leukaemia following the Chernobyl accident. However, different forms of childhood leukaemia may not be equally susceptible to radiation carcinogenesis. Infant leukaemia is a distinct form associated with a specific genetic abnormality. Outside the former Soviet Union, contamination resulting from the Chernobyl accident has been highest in Greece and Austria and high also in the Scandinavian countries(1-4). All childhood leukaemia cases diagnosed throughout Greece since 1 January 1980 have been recorded. Here we report that infants exposed in utero to ionizing radiation from the Chernobyl accident had 2.6 limes the incidence of leukaemia compared to unexposed children (95% confidence interval, 1.4 to 5.1; P approximate to 0.003), and those born to mothers residing in regions with high radioactive fallout were at higher risk of developing infant leukaemia. No significant difference in leukaemia incidence was found among children aged 12 to 47 months. Preconceptional irradiation had no demonstrable effect on leukaemia risk at any of the studied age groups. [References: 28]
机译：切尔诺贝利事故后，尚无儿童白血病增加的文献报道。然而，不同形式的儿童白血病可能不一样容易受到放射致癌作用的影响。婴儿白血病是与特定遗传异常相关的独特形式。在前苏联以外，切尔诺贝利事故造成的污染在希腊和奥地利最高，在斯堪的纳维亚国家也最高（1-4）。自1980年1月1日以来，已记录了整个希腊诊断出的所有儿童白血病病例。在这里，我们报告说，与未暴露的儿童相比，在子宫内暴露于切尔诺贝利事故电离辐射的婴儿患白血病的发生率为2.6石灰（95％的置信区间为1.4至5.1； P约为0.003），以及居住在该地区的母亲所生的婴儿放射性辐射高的婴儿患婴儿白血病的风险更高。在12到47个月大的儿童中，白血病的发生率没有显着差异。在任何研究的年龄组中，孕前照射对白血病风险均无明显影响。 [参考：28]

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