Genes from zebraflsh screens

Nigel Holder; Andrew McMahon

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Genes from zebraflsh screens

机译：斑马鱼筛选的基因

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LARGE-scale genetic screens have had a major impact on our understanding of invertebrate and plant development, yet until now there has been no systematic analysis of vertebrate embryogenesis. In a special issue of Development (VoL 123, December 1996), Janni Nusslein-Volhard and Wolfgang Driever's groups report the identification of several thousand new mutants in the zebrafish Danio rerio; the mutations occur in hundreds of genes, leading to a range of developmental defects. These papers have been eagerly anticipated in the vertebrate-development community, but how do the results match up to the high expectations, and what can we learn from them?

机译：大规模的基因筛查对我们对无脊椎动物和植物发育的理解产生了重大影响，但迄今为止，还没有对脊椎动物胚胎发生的系统分析。 Janni Nusslein-Volhard和Wolfgang Driever的研究小组在《发展》杂志（VoL 123，1996年12月）中报告了在斑马鱼Danio rerio中鉴定出数千个新突变体的信息。突变发生在数百个基因中，导致一系列发育缺陷。这些论文已经在脊椎动物开发界热切期盼，但是结果如何与高期望值相符，我们可以从中学到什么呢？

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《Nature》 |1996年第6609期|p.515-516|共2页
作者
Nigel Holder; Andrew McMahon;
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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1. Expression of long-chain polyunsaturated fatty acid (LC-PUFA) biosynthesis genes during zebraflsh Danio rerio early embryogenesis [J] . Oscar Monroig, Josep Rotllant, Elisa Sanchez Biochimica et Biophysica Acta. Molecular and cell biology of Lipids . 2009,第11期

机译：长链多不饱和脂肪酸（LC-PUFA）生物合成基因在斑马鱼Danio rerio早期胚胎发生过程中的表达
2. Zebraflsh z-otu, a novel Otu and Tudor domain-containing gene, is expressed in early stages of oogenesis and embryogenesis [J] . Mo SJ, Song P, Lv DY, Biochimica et biophysica acta. Gene structure and expression . 2005,第1a3期

机译：Zebraflsh z-otu是一种新的包含Otu和Tudor域的基因，在卵子发生和胚胎发生的早期阶段表达
3. Multigenerational reproduction and developmental toxicity, and HPG axis gene expression study on environmentally-relevant concentrations of nonylphenol in zebraflsh [J] . Dong Sun, Qi Chen, Bo Zhu, Science of the total environment . 2021,第Apra10期

机译：斑马夫苯酚环苯酚对环境相关浓度的多杀生殖繁殖和发育毒性及其肝轴基因表达研究
4. Neurogenesis in zebraflsh embryo cell cultures [C] . Natalia N. Singh, David W. Barnes Annual Meeting of the Japanese Association for Animal Cell Technology . 2002

机译：斑马夫胚胎细胞培养中的神经发生
5. Genetic screens for p53 pathway genes in zebrafish: the identification and characterization of novel gene wdr43. [D] . George, Stephen Alexander. 2011

机译：斑马鱼p53途径基因的遗传筛选：新基因wdr43的鉴定和表征。
6. The Network of Cancer Genes (NCG): a comprehensive catalogue of known and candidate cancer genes from cancer sequencing screens [O] . Dimitra Repana, Joel Nulsen, Lisa Dressler, 2019

机译：癌症基因网络（NCG）：来自癌症测序筛选的已知和候选癌症基因的全面目录
7. How many genes are part of the oscillatory network regulating somitogenesis? Developmental analysis and mathematical modeling of genes identified in functional genomic screens [O] . Eckalbar Walter, Sewell Will, Smith Allanceson, 2009

机译：振荡网络调节体细胞发生的基因有多少？在功能基因组筛选中鉴定的基因的发育分析和数学建模

Genes from zebraflsh screens

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