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首页> 外文期刊>Nature >Quantal-like current fluctuations induced by odorants in olfactory receptor cells.
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Quantal-like current fluctuations induced by odorants in olfactory receptor cells.

机译：嗅觉受体细胞中的气味诱导的类似量子的电流波动。

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摘要

Many sensory systems have evolved signal detection capabilities that are limited only by the physical attributes of the stimulus. For example, 'hair' cells of the inner ear can detect displacements of atomic dimensions. Likewise, both in vertebrates and in invertebrates photoreceptors can detect a single photon. The olfactory stimulus also has a quantal unit, the single odorant molecule. Insects are reportedly able to detect a single pheromone molecule, whereas quantal responses in vertebrate olfactory receptor cells have not been reported yet. Psychophysical measurements indicate that a minimum of 50 odorant molecules are necessary for human olfactory detection, suggesting that an individual receptor may be activated by a single odorant molecule. We report here measurements of current fluctuations induced by odorants that suggest a quantal event of about 0.3-1 pA, presumably triggered by the binding of a single odorant molecule.
机译：许多感觉系统已经发展了信号检测功能，该功能仅受刺激的物理属性限制。例如，内耳的“毛发”细胞可以检测原子尺寸的位移。同样，在脊椎动物和无脊椎动物中，感光器都可以检测到单个光子。嗅觉刺激也有一个定量单位，即单个气味分子。据报道，昆虫能够检测单个信息素分子，而脊椎动物嗅觉受体细胞中的定量反应尚未见报道。心理物理测量表明，至少50个气味分子对于人类嗅觉检测是必需的，这表明单个受体可以被单个气味分子激活。我们在这里报告了由增香剂引起的电流波动的测量结果，表明约0.3-1 pA的定量事件，大概是由单个增香剂分子的结合触发的。

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