Gene therapy cures leukaemia in eight days

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Gene therapy cures leukaemia in eight days

机译：基因疗法可在八天内治愈白血病

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Within just eight days of starting a novel gene therapy, David Aponte's "incurable" leukaemia had vanished. For four other patients, the same happened within eight weeks, although one later died from a blood clot unrelated to the treatment, and another after relapsing. The cured trio, who were all previously diagnosed with usually fatal relapses of acute lymphoblastic leukaemia, have now been in remission for between 5 months and 2 years. Michel Sadelain of the Memorial Sloan-Kettering Cancer Center in

机译：在开始一种新型基因疗法的短短八天之内，大卫·阿庞特的“无法治愈的”白血病就消失了。对于另外四名患者，同样的情况发生在八周之内，尽管一名后来死于与治疗无关的血块，另一名死于复发。治愈后的三人先前都被诊断出通常会致命的急性淋巴细胞白血病复发，现在已经缓解了5个月至2年。斯隆-凯特琳纪念癌症中心的Michel Sadelain

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《New scientist》 |2013年第2910期|10-10|共1页
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收录信息美国《科学引文索引》(SCI);美国《化学文摘》(CA);
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正文语种 eng
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1. The acute promyelocytic leukaemia success story: curing leukaemia through targeted therapies. [J] . K L Rice, H de Thé Journal of Internal Medicine . 2014,第1期

机译：急性早幼粒细胞白血病成功案例：通过靶向疗法治愈白血病。
2. Secondary leukaemia after cure for locally advanced NSCLC: alkylating type secondary leukaemia after induction therapy with docetaxel and carboplatin for NSCLC IIIB. [J] . Griesinger F, Metz M, Trumper L, Lung cancer: Journal of the International Association for the Study of Lung Cancer . 2004,第2期

机译：局部晚期NSCLC治愈后的继发性白血病：用多西他赛和卡铂诱导治疗NSCLC IIIB后的烷基化型继发性白血病。
3. Acute myeloid leukaemia with maturation demonstrates persistent disease with prominent megakaryoblastic differentiation 16?days following induction chemotherapy: an intra‐myeloid lineage switch mediated by chemotherapy‐induced clonal selection [J] . Zhao Yue, Maule Jake, McCracken Jenna, British Journal of Haematology . 2020,第3期

机译：具有成熟的急性髓性白血病表明患有突出的巨大噬菌体分化16？诱导化疗后的天数：由化疗诱导的克隆选择介导的骨髓内谱系开关
4. EFFECT OF THE SELECTIVE TREATMENT OF CLINICAL MASTITIS BASED IN ON- FARM CULTURE RESULTS ON THE RISK TO RECEIVE SECONDARY THERAPY, DAYS TO CLINICAL CURE AND DAYS OUT OF THE TANK [C] . Alfonso Lago, Sandra Godden, Russ Bey, Annual Meeting of the National Mastitis Council . 2009

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5. The Distribution of Change over Time in Metabolic, Inflammatory, and Immune Parameters in HCV-monoinfected and HIV/HCV-coinfected Patients Cured of Hepatitis C Virus by Direct-Acting Antiviral Therapy [D] . Emmanuel, Benjamin. 2018

机译：通过直接作用抗病毒治疗，在HCV-单染料和HCV / HCV / HCV-焦收的患者中的代谢，炎症和免疫参数随时间随时间的分布，通过直接作用抗病毒治疗治愈丙型肝炎病毒
6. Clinical significance of plasmacytosis in the day+14 bone marrow of patients with acute myeloid leukaemia undergoing induction chemotherapy [O] . Nada Al‐Shughair, Ghuzayel Al‐Dawsari, Martin Gyger, 2007

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7. Wilms tumour 1 peptide vaccine as a cure-oriented post-chemotherapy strategy for patients with acute myeloid leukaemia at high risk of relapse [O] . Jun Nakata, Yoshiki Nakae, Manabu Kawakami, 2017

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8. Acute Lymphocytic Leukaemia in Children in the Netherlands. Results of Treatment According to Protocol ALL II (Dutch Childhood Leukaemia Study Group) and Immunological Studies after Cessation of Therapy [R] . Does-van den Berg, A. 1980

机译：荷兰儿童急性淋巴细胞白血病。根据方案aLL II（荷兰儿童白血病研究组）和停止治疗后的免疫学研究的治疗结果

Gene therapy cures leukaemia in eight days

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